Evidence map›Paper›PMID 31557719›Full record

ArticleRedox biology2020

A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.

Karl Köhnlein, Nadine Urban, David Guerrero-Gómez, Holger Steinbrenner, Pavel Urbánek, Josephine Priebs, Philipp Koch, Christoph Kaether, Antonio Miranda-Vizuete, Lars-Oliver Klotz

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. International journal of molecular sciences · 2024
    Article
  6. Review
  7. Review
  8. Selenium-EnrichedAntioxidants (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Article
  11. Exploring the mechanisms of host-specificity of a hyperparasitic bacterium (Frontiers in cellular and infection microbiology · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Karl KöhnleinInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich-Schiller-Universität Jena, Jena, Germany; Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.
Nadine UrbanInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich-Schiller-Universität Jena, Jena, Germany.
David Guerrero-GómezInstituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain.
Holger SteinbrennerInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich-Schiller-Universität Jena, Jena, Germany.
Pavel UrbánekInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich-Schiller-Universität Jena, Jena, Germany.
Josephine PriebsInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich-Schiller-Universität Jena, Jena, Germany.
Philipp KochLeibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.
Christoph KaetherLeibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.
Antonio Miranda-VizueteInstituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain.
Lars-Oliver KlotzInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich-Schiller-Universität Jena, Jena, Germany. Electronic address: lars-oliver.klotz@uni-jena.de.
Friedrich Schiller University Jena · DELeibniz Institute on Aging - Fritz Lipmann Institute (FLI) · DEInstituto de Biomedicina de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human selenium-binding protein 1 (SELENBP1) was originally identified as a protein binding selenium, most likely as selenite. SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation of methanethiol, a methionine catabolite, generating hydrogen sulfide (H

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCytoplasmDrug ResistanceGene Expression RegulationHumansLongevityMembrane ProteinsOxidative StressParaquatSelenious AcidSelenium-Binding ProteinsStructural Homology, ProteinCaenorhabditis elegans Proteinsccar-1 protein, C elegansMembrane ProteinsParaquatSELENBP1 protein, humanSelenious AcidSelenium-Binding ProteinsCaenorhabditis elegansLifespanSelenium-binding proteinStress signaling

Identifiers

PMID31557719
PMCPMC6812014
OpenAlexW2972873837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.