Evidence map›Paper›PMID 31557021›Full record

ArticleJournal of natural products2019

PepSAVI-MS Reveals a Proline-rich Antimicrobial Peptide in

Tessa B Moyer, Lilian R Heil, Christine L Kirkpatrick, Dennis Goldfarb, William A Lefever, Nicole C Parsley, Andrew J Wommack, Leslie M Hicks

Abstract read
In one paragraph

Article in Journal of natural products, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  15. Multiple Classes of Antimicrobial Peptides inJournal of natural products · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tessa B Moyer
Lilian R Heil
Christine L Kirkpatrick
Dennis Goldfarb
William A LefeverDepartment of Chemistry , High Point University , High Point , North Carolina United States.
Nicole C Parsley
Andrew J WommackDepartment of Chemistry , High Point University , High Point , North Carolina United States.ORCID 0000-0002-0889-9108

Funding

PepSAVI-MS for discovery of novel botanical antimicrobial peptidesR01GM125814 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HICKS, LESLIE M. · 2018 to 2022
$1.6M
NIGMS NIH HHS R01 GM125814
6 · The paper itself

Abstract

Traditional medicinal plants are a rich source of antimicrobials; however, the bioactive peptide constituents of most ethnobotanical species remain largely unexplored. Herein, PepSAVI-MS, a mass spectrometry-based peptidomics pipeline, was implemented for antimicrobial peptide (AMP) discovery in the medicinal plant

Indexed as

AmaranthusAntimicrobial Cationic PeptidesMass SpectrometryProlineAntimicrobial Cationic PeptidesProline

Identifiers

PMID31557021
PMCPMC6874829

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.