ArticleJournal of applied physiology (Bethesda, Md. : 1985)2020
Shear wave velocity is sensitive to changes in muscle stiffness that occur independently from changes in force.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Characterizing Musculoskeletal Tissue Mechanics Based on Shear Wave Propagation: A Systematic Review of Current Methods and Reported Measurements.Annals of biomedical engineering · 2022Pooled it
- The role of muscle ultrasound in stroke rehabilitation: a review of calf muscle alterations and clinical implications.Frontiers in neurologyPooled it
- Active release techniquesJournal of back and musculoskeletal rehabilitation · 2026Trial
- Effects of Reduced Training Volume of Nordic Hamstring Exercise on Eccentric Knee Flexor Strength, and Fascicle Length and Stiffness of Biceps Femoris Long Head.Scandinavian journal of medicine & science in sports · 2025Trial
- Medial gastrocnemius stiffness contributes to active ankle joint stiffness and ground contact time in trained track-and-field athletes.European journal of applied physiology · 2026Article
- Electrical stimulation reduces post-exercise muscle stiffness and enhances flexibility in hamstring muscles.European journal of applied physiology · 2026Article
- Reliability of quadriceps and hamstring muscle stiffness measured by ultrasound shear wave elastography in patients with knee osteoarthritis.BMC musculoskeletal disorders · 2026Article
- Changes in Passive Muscle Stiffness Following Biceps Femoris Strain Injury in Track-and-Field Athletes: Cross-Sectional and Longitudinal Analyses.Scandinavian journal of medicine & science in sports · 2026Article
- Muscle Tendon Passive Parameter Estimation Using Musculoskeletal Optimal Control.Annals of biomedical engineering · 2026Article
- Achilles tendon ultrasound-derived properties of the dominant and non-dominant jumping leg of university basketball athletes: relation with performance, range of motion, and injury.Frontiers in sports and active living · 2026Article
- Mechanical characterization of an incompressible, strain-hardening, transversely isotropic material.Acta biomaterialia · 2026Article
- Critical-Size Muscle Defect Regeneration Using an Injectable Cell-Laden Nanofibrous Matrix: An Ex Vivo Mouse Hindlimb Organ Culture Study.International journal of molecular sciences · 2025Article
- Patellar Tendon Properties and Unilateral Jump Performance in Junior Elite Volleyball Players With Patellar Tendinopathy.European journal of sport science · 2025Article
- Cold Compression and Ischemic Preconditioning With Ice Therapy Enhance Muscle Recovery and Functionality Post-Exercise: A Randomized Study.Annals of rehabilitation medicine · 2025Article
- In vivo tibialis anterior muscle mechanics through force estimation using ankle joint moment and shear wave elastography.Scientific reports · 2025Article
- Is nerve-directed stretching effective for improving of ankle joint flexibility and tissue stiffness in older men?Journal of clinical biochemistry and nutrition · 2025Article
- Effects of chronic low-frequency pulsed magnetic fields exposure on the contractility and morphology of biceps brachii in healthy adults-a randomized controlled, double-blind trial.Frontiers in medicine · 2025Article
- Article
- Test-retest reliability and follow-up of muscle magnetic resonance elastography in adults with and without muscle diseases.Journal of cachexia, sarcopenia and muscle · 2024Article
- Characterizing Mechanical Changes in the Biceps Brachii Muscle in Mild Facioscapulohumeral Muscular Dystrophy Using Shear Wave Elastography.Diagnostics (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Clinical assessments for many musculoskeletal disorders involve evaluation of muscle stiffness, although it is not yet possible to obtain quantitative estimates from individual muscles. Ultrasound elastography can be used to estimate the material properties of unstressed, homogeneous, and isotropic materials by tracking the speed of shear wave propagation; these waves propagate faster in stiffer materials. Although elastography has been applied to skeletal muscle, there is little evidence that shear wave velocity (SWV) can directly estimate muscle stiffness since this tissue violates many of the assumptions required for there to be a direct relationship between SWV and stiffness. The objective of this study was to evaluate the relationship between SWV and direct measurements of muscle force and stiffness in contracting muscle. Data were collected from six isoflurane-anesthetized cats. We measured the short-range stiffness in the soleus via direct mechanical testing in situ and SWV via ultrasound imaging. Measurements were taken during supramaximal activation at optimum muscle length, with muscle temperature varying between 26°C and 38°C. An increase in temperature causes a decrease in muscle stiffness at a given force, thus decoupling the tension-stiffness relationship normally present in muscle. We found that increasing muscle temperature decreased active stiffness from 4.0 ± 0.3 MPa to 3.3 ± 0.3 MPa and SWV from 16.9 ± 1.5 m/s to 15.9 ± 1.6 m/s while force remained unchanged (mean ± SD). These results demonstrate that SWV is sensitive to changes in muscle stiffness during active contractions. Future work is needed to determine how this relationship is influenced by changes in muscle structure and tension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.