ArticleJournal of consulting and clinical psychology2019
Diverse diagnostic profiles associated with prescription opioid use disorder in a nationwide sample: One crisis, multiple needs.
Article in Journal of consulting and clinical psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Optimizing opioid use disorder treatment with naltrexone or buprenorphine.Drug and alcohol dependence · 2021Trial
- Polysubstance use patterns among individuals applying for opioid use disorder treatment in the U.S.Journal of substance use · 2025Article
- Differential etiologic associations of heroin use and prescription opioid misuse with psychopathology.Journal of psychopathology and clinical science · 2024Article
- Optimally Choosing Medication Type for Patients With Opioid Use Disorder.American journal of epidemiology · 2023Article
- Classifying risky cannabis involvement in young adults using the Marijuana Consequences Questionnaire (MACQ).Addictive behaviors · 2022Article
- Subtypes in Patients Taking Prescribed Opioid Analgesics and Their Characteristics: A Latent Class Analysis.Frontiers in psychiatry · 2022Article
- Problematic Opioid Use: A Scoping Literature Review of Profiles.Substance abuse : research and treatment · 2022Article
- The latent class structure of substance use in US adults 50 years and older.International journal of geriatric psychiatry · 2021Article
- Opioid Misuse Among American Indian Adolescents.American journal of public health · 2021Article
- Prescription opioid misuse motive latent classes: outcomes from a nationally representative US sample.Epidemiology and psychiatric sciences · 2020Article
- Prescription Drug Misuse: Taking a Lifespan Perspective.Substance abuse : research and treatment · 2020Review
- Modeling SARS-CoV-2 infection in individuals with opioid use disorder with brain organoids.Journal of tissue engineeringReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe opioid crisis has had devastating effects on individuals and communities, and it has rapidly increased in severity. However, we still lack nationally representative information on the diversity of comorbidity patterns among prescription opioid use disorder (P-OUD), other substance use disorders (SUDs), and psychopathology using the newest edition of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association, 2013). This impedes planning for multiple aspects of intervention, including society-wide allocation of treatment resources, program design at individual treatment centers, and personalized care to individual patients.
methodTo address this critical gap in information, we evaluated clinical profiles of American adults via latent class analysis in a large, recently collected epidemiological dataset that uses structured diagnostic assessment for DSM-5 psychopathology (National Epidemiologic Survey on Alcohol and Related Conditions-III; N = 36,309). Variables considered for profiles included lifetime diagnosis for multiple SUDs, various externalizing and internalizing conditions, and demographic variables. We then associated clinical profiles with demographic variables and functional impairment.
resultsComorbid psychopathology and other SUDs were common in latent classes with elevated and very high rates of P-OUD. To illustrate, alcohol use disorder rates were greater than 45%, and posttraumatic stress disorder rates were greater than 28% in classes with higher P-OUD rates. Higher P-OUD rates were associated with White/non-Hispanic and American Indian/Alaska Native populations. Relationships between P-OUD rates and functional impairment were inconsistent.
conclusionMany current treatment delivery systems are not designed to accommodate the heterogeneous profiles associated with high P-OUD rates. We provide specific suggestions for improvements to the mental health service system, individual clinical care programs, and future research approaches. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.