Evidence map›Paper›PMID 31556333›Full record

ReviewThe British journal of radiology2020

Physical advantages of particles: protons and light ions.

Oliver Jäkel

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  9. Article
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  11. Review
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  13. Review
  14. Article
  15. Neuroprotective Effects of Ultra-High Dose Rate FLASH Bragg Peak Proton Irradiation.International journal of radiation oncology, biology, physics · 2022
    Article
  16. The history of ion beam therapy in Germany.Zeitschrift fur medizinische Physik · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Proton therapy special feature: introductory editorial.The British journal of radiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Oliver JäkelHeidelberg Ion-Beam Therapy Center (HIT) at the University Hospital Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6056-9747
German Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proton and ion beam therapy has been introduced in the Lawrence Berkeley National Laboratory in the mid-1950s, when protons and helium ions have been used for the first time to treat patients. Starting in 1972, the scientists at Berkeley also were the first to use heavier ions (carbon, oxygen, neon, silicon and argon ions). The first clinical ion beam facility opened in 1994 in Japan and since then, the interest in radiotherapy with light ion beams has been increasing slowly but steadily, with 13 centers in clinical operation in 2019. All these centers are using carbon ions for clinical application.The article outlines the differences in physical properties of various light ions as compared to protons in view of the application in radiotherapy. These include the energy loss and depth dose properties, multiple scattering, range straggling and nuclear fragmentation. In addition, the paper discusses differences arising from energy loss and linear energy transfer with respect to their biological effects.Moreover, the paper reviews briefly the existing clinical data comparing protons and ions and outlines the future perspectives for the clinical use of ions like oxygen and helium.

Indexed as

Heavy Ion RadiotherapyLinear Energy TransferProton TherapyAbsorption, RadiationAlgorithmsCarbonHeliumHumansNeoplasmsOxygenPilot ProjectsRadiobiologyRadiotherapy DosageScattering, RadiationCarbonHeliumOxygen

Identifiers

PMID31556333
PMCPMC7066975
OpenAlexW2975917903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.