ReviewSurgery today2020
Portal flow modulation in living donor liver transplantation: review with a focus on splenectomy.
Review in Surgery today, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Asian Pacific Association for the Study of the Liver clinical practice guidelines on liver transplantation.Hepatology international · 2024Guideline
- Outcomes of living donor liver transplantation in elderly Egyptian patients: a retrospective study.Langenbeck's archives of surgery · 2026Article
- Risk Factors for Small-for-Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living-Donor Liver Transplantation.Annals of gastroenterological surgery · 2026Article
- A graft-to-recipient weight ratio of less than 0.7% under portal venous hemodynamics monitoring is a risk factor for early graft loss after living donor liver transplantation.Surgery today · 2025Article
- [Clinical outcomes of small-size grafts in auxiliary liver transplantation for the treatment of portal hypertension].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- Prediction of graft loss in living donor liver transplantation during the early postoperative period.PLoS computational biology · 2025Article
- The small-for-size syndrome in living donor liver transplantation: current management.Updates in surgery · 2025Review
- Graft inflow modulation in recipients with portal hypertension.Updates in surgery · 2025Review
- Splenectomy and risk of hepatocellular carcinoma.World journal of hepatology · 2025Review
- Splenic Artery Ligation: Effects on Portal Flow and Hypersplenism in Living Donor Liver Transplantation.Annals of transplantation · 2025Article
- Clinical validation of preoperative serum markers for liver fibrosis in living donor liver transplantation recipients.Surgery today · 2025Article
- Anatomical limits in living donor liver transplantation.Korean journal of transplantation · 2022Review
- Liver transplantation with simultaneous splenectomy increases risk of cancer development and mortality in hepatocellular carcinoma patients.World journal of gastrointestinal surgery · 2022Article
- Current review of machine perfusion in liver transplantation from the Japanese perspective.Surgery today · 2022Review
- Volume and flow modulation strategies to mitigate post-hepatectomy liver failure.Frontiers in oncology · 2022Review
- Which is better to use "body weight" or "standard liver weight", for predicting small-for-size graft syndrome after living donor liver transplantation?Annals of gastroenterological surgery · 2021Article
- Low-Pressure Tactic: A Novel Intrahepatic Shunt Improves Outcomes in Experimental Small-for-Size Syndrome.Digestive diseases and sciences · 2020Article
- Post-transplant inflow modulation for early allograft dysfunction after living donor liver transplantation.Surgical case reports · 2020Article
- Predictor of outcome after living donor liver transplantation for patients with hepatocellular carcinoma beyond the Japan criteria.Annals of gastroenterological surgery · 2020Article
- The efficacy of intraoperative indocyanine green fluorescence angiography in gastric cancer operation after living donor liver transplantation: A case report.International journal of surgery case reports · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small-for-size graft (SFSG) syndrome after living donor liver transplantation (LDLT) is the dysfunction of a small graft, characterized by coagulopathy, cholestasis, ascites, and encephalopathy. It is a serious complication of LDLT and usually triggered by excessive portal flow transmitted to the allograft in the postperfusion setting, resulting in sinusoidal congestion and hemorrhage. Portal overflow injures the liver directly through nutrient excess, endothelial activation, and sinusoidal shear stress, and indirectly through arterial vasoconstriction. These conditions may be attenuated with portal flow modulation. Attempts have been made to control excessive portal flow to the SFSG, including simultaneous splenectomy, splenic artery ligation, hemi-portocaval shunt, and pharmacological manipulation, with positive outcomes. Currently, a donor liver is considered a SFSG when the graft-to-recipient weight ratio is less than 0.8 or the ratio of the graft volume to the standard liver volume is less than 40%. A strategy for transplanting SFSG safely into recipients and avoiding extensive surgery in the living donor could effectively address the donor shortage. We review the literature and assess our current knowledge of and strategies for portal flow modulation in LDLT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.