Evidence map›Paper›PMID 31555652›Full record

ReviewFrontiers in nutrition2019

At the Interface of Lifestyle, Behavior, and Circadian Rhythms: Metabolic Implications.

Seul-A Bae, Ming Zhu Fang, Vinod Rustgi, Helmut Zarbl, Ioannis P Androulakis

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04813146 (Role of Synchronized Lifestyle Modification Program on Diabetic Peripheral Neuropathy Patients Taking Oral Hypoglycemics and GLP-1 Analogues), which is not on this map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04813146 nacompletednot on this mapstarted 2021, after this paper: background citation

Role of Synchronized Lifestyle Modification Program on Diabetic Peripheral Neuropathy Patients Taking Oral Hypoglycemics and GLP-1 Analogues

TypeinterventionalSponsorRiphah International UniversityRan2021 to 2022Enrolled216ConditionsDiabetic NeuropathiesArmsSLP, SLP along with Physiotherapy, Physiotherapy
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Integrated Analysis ofBiomolecules · 2026
    Article
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  13. Review
  14. Review
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  16. Article
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  18. Circadian rhythms: pervasive, and often times evasive.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seul-A BaeChemical and Biochemical Engineering Department, Rutgers University, Piscataway, NJ, United States.
Ming Zhu FangDepartment of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, Piscataway, NJ, United States.
Vinod RustgiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
Helmut ZarblDepartment of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, Piscataway, NJ, United States.
Ioannis P AndroulakisChemical and Biochemical Engineering Department, Rutgers University, Piscataway, NJ, United States.

Funding

CORTICOSTEROID PHARMACOKINETICS/DYNAMICSR01GM024211 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI JUSKO, WILLIAM J. · 1985 to 2018
$4.7M
Mechanistic Pharmacokinetics and PharmacodynamicsR35GM131800 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI JUSKO, WILLIAM J. · 2019 to 2023
$2.9M
NIGMS NIH HHS R01 GM024211
6 · The paper itself

Abstract

Nutrient metabolism is under circadian regulation. Disruption of circadian rhythms by lifestyle and behavioral choices such as work schedules, eating patterns, and social jetlag, seriously impacts metabolic homeostasis. Metabolic dysfunction due to chronic misalignment of an organism's endogenous rhythms is detrimental to health, increasing the risk of obesity, metabolic and cardiovascular disease, diabetes, and cancer. In this paper, we review literature on recent findings on the mechanisms that communicate metabolic signals to circadian clocks and

Indexed as

chronodisruptioncircadian rhythmsmetabolic syndromemetabolismshift work

Identifiers

PMID31555652
PMCPMC6722208

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.