Evidence map›Paper›PMID 31555456›Full record

ArticleCanadian journal of kidney health and disease2019

Can Split Renal Volume Assessment by Computed Tomography Replace Nuclear Split Renal Function in Living Kidney Donor Evaluations? A Systematic Review and Meta-Analysis.

Steven Habbous, Carlos Garcia-Ochoa, Gary Brahm, Chris Nguan, Amit X Garg

Abstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Steven HabbousDepartment of Epidemiology and Biostatistics, Western University, London, ON, Canada.ORCID https://orcid.org/0000-0002-9650-9105
Carlos Garcia-OchoaDepartment of Epidemiology and Biostatistics, Western University, London, ON, Canada.ORCID https://orcid.org/0000-0002-3960-3664
Gary BrahmDepartment of Radiology, London Health Sciences, ON, Canada.
Chris NguanVancouver General Hospital, BC, Canada.
Amit X GargDepartment of Epidemiology and Biostatistics, Western University, London, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs part of their living kidney donor assessment, all living donor candidates complete a computed tomography (CT) angiogram, but some also receive a nuclear renogram for split renal function (SRF%).

objectiveWe considered whether split renal volume (SRV%) assessed by CT can predict SRF%.

designSystematic review and meta-analysis.

settingLiving donor candidates undergoing evaluation as potential living kidney donors. PATIENTS: Living donor candidates who received both a nuclear renogram for split function and CT for SRV as part of their living donor work-up. MEASUREMENTS: Split renal volume from CT scans and SRF from nuclear renography.

methodsWe performed a systematic review and meta-analysis of the literature, abstracting data and digitizing plots where possible. We searched Medline, EMBASE, and the Cochrane Library. We added data from donor candidates assessed in London, Ontario from 2013 to 2016. We used fixed and random-effects models to pool Fisher's

resultsAfter pooling 19 studies (n = 1479), we obtained a pooled correlation of LIMITATIONS: Most studies were retrospective and measured SRV and SRF only on selected living donor candidates. Efficiency gains in removing the SRF from the evaluation will depend on the transplant program.

conclusionSplit renal volume has the potential to replace SRF for some candidates. However, it is uncertain whether it can do so reliably and routinely across different transplant centers. The impact on clinical decision-making needs to be assessed in well-designed prospective studies.

trial registrationThe digitized data are registered with Mendeley Data (doi10.17632/dyn2bfgxxj.2).

Indexed as

computed tomographyliving kidney donorsplit kidney volumesplit renal function

Identifiers

PMID31555456
PMCPMC6753513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.