Evidence map›Paper›PMID 31555385›Full record

ArticleExperimental and therapeutic medicine2019

miR-370 inhibits the oxidative stress and apoptosis of cardiac myocytes induced by hydrogen peroxide by targeting FOXO1.

Zhanjun Qiu, Lei Wang, Huaiyu Mao, Feng Xu, Bin Sun, Xinbao Lian, Jiali Wang, Feng Kong, Lina Wang, Yuguo Chen

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Article
  10. MicroRNA and ROS Crosstalk in Cardiac and Pulmonary Diseases.International journal of molecular sciences · 2020
    Review
  11. Article
  12. microRNA Expression Profiles in Myocardium of High-Fat Diet-Induced Obesity Rat.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Zhanjun QiuDepartment of Emergency Medicine and Chest Pain Center, Affiliated Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Lei WangDepartment of Emergency and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250014, P.R. China.
Huaiyu MaoDepartment of Emergency Medicine, The Second People's Hospital of Dongying, Dongying, Shandong 257335, P.R. China.
Feng XuDepartment of Emergency Medicine and Chest Pain Center, Affiliated Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Bin SunDepartment of Emergency Medicine, Yidu Center Hospital of Weifang, Weifang, Shandong 262500, P.R. China.
Xinbao LianDepartment of Emergency and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250014, P.R. China.
Jiali WangDepartment of Emergency Medicine and Chest Pain Center, Affiliated Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Feng KongDepartment of Central Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Lina WangDepartment of Clinical Laboratory Medicine, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Yuguo ChenDepartment of Emergency Medicine and Chest Pain Center, Affiliated Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Qilu Hospital of Shandong University · CNShandong University of Traditional Chinese Medicine · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CNSecond Hospital of Shandong University · CNXian Yang Central Hospital · CNYidu Central Hospital of Weifang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction, one of the main factors that threatens human health, leads to cardiac cell death. Myocardial cells suffer ischemia and hypoxia for a long period of time, which can lead to irreversible cell death or apoptosis and cardiac dysfunction. MicroRNAs (miRs) have been reported to play an important role in a wide range of biological processes in cardiac myocytes, which respond to inflammation and oxidative stress. The aim of the present study was to investigate the effect of miR-370 on oxidative stress and apoptosis of cardiac myocytes in ischemic H9C2 cells induced by hydrogen peroxide (H

Indexed as

apoptosisForkhead box O1microRNA-370myocardial infarctionoxidative stress

Identifiers

PMID31555385
PMCPMC6755418
OpenAlexW2967550657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.