Evidence map›Paper›PMID 31555336›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2019

Cytotoxic effects of

Benyamin Shahbazi, Zahra Salehi Najafabadi, Hamidreza Goudarzi, Mahnaz Sajadi, Fatemeh Tahoori, Masoumeh Bagheri

Open access · goldAbstract read
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Cytotoxic effects of crotoxin fromThe journal of venomous animals and toxins including tropical diseases · 2024
    Article
  4. Evaluation ofArchives of Razi Institute · 2022
    Article
  5. Pharmacological Characterisation ofInternational journal of molecular sciences · 2021
    Article
  6. Effect ofThe journal of venomous animals and toxins including tropical diseases · 2020
    Article
  7. Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (The journal of venomous animals and toxins including tropical diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benyamin ShahbaziPayame Noor University of Tehran Shargh, Tehran, Iran.
Zahra Salehi NajafabadiRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran.ORCID 0000-0002-0658-9966
Hamidreza GoudarziRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran.
Mahnaz SajadiTofigh Daru Research and Engineering Company, Tehran, Iran.
Fatemeh TahooriRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran.
Masoumeh BagheriRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran.
Razi Vaccine and Serum Research Institute · IRIran Khodro (Iran) · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies have pointed out that certain snake venoms contain compounds presenting cytotoxic activities that selectively interfere with cancer cell metabolism. In this study,

methodsLung cancer cells (A549) and normal fibroblast cells (Hu02) were treated with the

resultsThe treatment of cells with HPLC fraction 21 (25-35 kDa) of

conclusionHPLC fraction 21 at low concentrations displayed promising anticancer properties with apoptosis induction in the lung cancer cells. This fraction may, therefore, be considered a promising candidate for further studies.

Indexed as

ApoptosisCytotoxicityHPLC fractionsPersian horned viperPseudocerastes persicus venom

Identifiers

PMID31555336
PMCPMC6748451
OpenAlexW2972343674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.