Evidence map›Paper›PMID 31555296›Full record

ArticleFrontiers in immunology2019

Rhoptry and Dense Granule Secreted Effectors Regulate CD8

Leah M Rommereim, Barbara A Fox, Kiah L Butler, Viviana Cantillana, Gregory A Taylor, David J Bzik

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. The Distribution ofMicroorganisms · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Dense granule protein 3 ofFrontiers in immunology · 2023
    Article
  8. Variation in CD8 T cell IFNγ differentiation to strains ofFrontiers in cellular and infection microbiology · 2023
    Article
  9. Article
  10. Review
  11. Mining the Proteome ofAnimals : an open access journal from MDPI · 2022
    Review
  12. Article
  13. Article
  14. Cutting Edge: CD36 Mediates Phagocyte Tropism and Avirulence ofJournal of immunology (Baltimore, Md. : 1950) · 2021
    Article
  15. Article
  16. iTRAQ-Based Phosphoproteomic Analysis ofFrontiers in cellular and infection microbiology · 2020
    Article
  17. Key Limitations and New Insights Into theFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Leah M RommereimDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Barbara A FoxDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Kiah L ButlerDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Viviana CantillanaDivision of Geriatrics, Departments of Medicine, Molecular Genetics and Microbiology, and Immunology, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, United States.
Gregory A TaylorDivision of Geriatrics, Departments of Medicine, Molecular Genetics and Microbiology, and Immunology, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, United States.
David J BzikDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.
Dartmouth College · USDuke Medical Center · USDuke University Hospital · US

Funding

Role of IRGM proteins in immunity to enteric bacteriaR01AI145929 · NIAID · DUKE UNIVERSITY · PI TAYLOR, GREGORY A · 2019 to 2023
$1.6M
Intravacuolar network dense granule protein biology in chronic Toxoplasma infectionR21AI152687 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2020 to 2021
$451k
Novel vacuole biology in chronic Toxoplasma infectionR21AI138501 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2020 to 2021
$451k
Novel virulence function in Toxoplasma chronic infectionR21AI131630 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2018 to 2019
$446k
Dense granule protein virulence factors in Toxoplasma gondii infectionR21AI108489 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2014 to 2015
$446k
Novel rhoptry protein function in chronic toxoplasma infectionR21AI129869 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2017 to 2018
$446k
Genetic models for latent Toxoplasma gondii infectionR21AI137118 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2018 to 2019
$446k
Parasite secreted proteins control host response to Toxoplasma gondii infectionR21AI104514 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2013 to 2014
$445k
Genetic dissection of the Toxoplasma gondii rhoptry kinomeR21AI097018 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2011 to 2012
$435k
Toxoplasma gondii GRA protein functionR21AI105563 · NIAID · DARTMOUTH COLLEGE · PI BZIK, DAVID J · 2013 to 2014
$433k
NIAID NIH HHS R01 AI145929NIAID NIH HHS R21 AI097018NIAID NIH HHS R21 AI104514NIAID NIH HHS R21 AI105563NIAID NIH HHS R21 AI108489NIAID NIH HHS R21 AI129869NIAID NIH HHS R21 AI131630NIAID NIH HHS R21 AI137118NIAID NIH HHS R21 AI138501NIAID NIH HHS R21 AI152687
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntigen PresentationAntigens, ProtozoanCD8-Positive T-LymphocytesMiceMice, Inbred C57BLProtein Serine-Threonine KinasesProtozoan ProteinsToxoplasmaToxoplasmosis, AnimalVacuolesAntigens, ProtozoanProtein Serine-Threonine KinasesProtozoan Proteinsantigen presentationdense granuleimmunity related GTPasesrhoptryToxoplasma gondii

Identifiers

PMID31555296
PMCPMC6742963
OpenAlexW2969573611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.