Evidence map›Paper›PMID 31555281›Full record

ArticleFrontiers in immunology2019

STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function.

Megan M Hanlon, Tatsiana Rakovich, Clare C Cunningham, Sharon Ansboro, Douglas J Veale, Ursula Fearon, Trudy McGarry

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.

  1. Pooled it
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  8. Journal of Cancer · 2026
    Article
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  11. STAT3 axis in cancer and cancer stem cells: From oncogenesis to targeted therapies.Biochimica et biophysica acta. Reviews on cancer · 2025
    Review
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Megan M HanlonMolecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland.
Tatsiana RakovichMolecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland.
Clare C CunninghamMolecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland.
Sharon AnsboroMolecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland.
Douglas J VealeCentre for Arthritis and Rheumatic Diseases, St. Vincent's University Hospital, UCD, Dublin, Ireland.
Ursula FearonMolecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland.
Trudy McGarryMolecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland.
Trinity College Dublin · IESt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Arthritis, RheumatoidCell AdhesionCells, CulturedCytokinesEndothelial CellsFibroblastsHumansJanus KinasesNeovascularization, PhysiologicOncostatin MPhosphorylationSignal TransductionSTAT3 Transcription FactorSynovial MembraneTumor Necrosis Factor-alphaCytokinesJanus KinasesOncostatin MSTAT3 protein, humanSTAT3 Transcription FactorTumor Necrosis Factor-alphacellular bioenergeticsJAK-STAT signalingpro-inflammatory cytokinesrheumatoid arthritissynovial fibroblasts

Identifiers

PMID31555281
PMCPMC6724663
OpenAlexW2968005098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.