Evidence map›Paper›PMID 31555249›Full record

ReviewFrontiers in microbiology2019

Scrub Typhus Pathogenesis: Innate Immune Response and Lung Injury During

Brandon Trent, James Fisher, Lynn Soong

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Analysis of the Epidemiological Characteristics and Risk Factors for Severe Progression of Scrub Typhus in the Dali Region of China.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Cavitary pulmonary tuberculosis withFrontiers in medicine · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brandon TrentDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
James FisherDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Lynn SoongDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · US

Funding

Biodefense Training ProgramT32AI060549 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ASHOK K CHOPRA, Janice J Endsley · 2004 to 2026
$3.0M
Pathogenic Mechanisms of Vascular Dysfunction in Scrub TyphusR01AI132674 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Yuejin Liang, LYNN SOONG · 2018 to 2026
$3.0M
Dysregulated type-1 and Vascular Responses in Scrub typhus PathogenesisR21AI117368 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOONG, LYNN · 2015 to 2016
$426k
NIAID NIH HHS R01 AI132674NIAID NIH HHS R21 AI117368NIAID NIH HHS T32 AI060549
6 · The paper itself

Abstract

Scrub typhus is an understudied, potentially lethal disease caused by infection with

Indexed as

acute respiratory distress syndromeendothelial cellmacrophageneutrophilOrientia tsutsugamushiscrub typhus

Identifiers

PMID31555249
PMCPMC6742975
OpenAlexW2969467773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.