Evidence map›Paper›PMID 31555136›Full record

ArticleFrontiers in pharmacology2019

Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Na

Mikhail Yu Myshkin, Roope Männikkö, Olesya A Krumkacheva, Dmitrii S Kulbatskii, Anton O Chugunov, Antonina A Berkut, Alexander S Paramonov, Mikhail A Shulepko, Matvey V Fedin, Michael G Hanna and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Mikhail Yu MyshkinShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Roope MännikköMRC Centre for Neuromuscular Diseases, Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom.
Olesya A KrumkachevaInternational Tomography Center SB RAS, Novosibirsk, Russia.
Dmitrii S KulbatskiiShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Anton O ChugunovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Antonina A BerkutShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Alexander S ParamonovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Mikhail A ShulepkoShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Matvey V FedinInternational Tomography Center SB RAS, Novosibirsk, Russia.
Michael G HannaMRC Centre for Neuromuscular Diseases, Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom.
Dimitri M KullmannDepartment of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, United Kingdom.
Elena G BagryanskayaN.N.Voroztsov Novosibirsk Institute of Organic Chemistry SB RAS, Novosibirsk, Russia.
Alexander S ArsenievShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Mikhail P KirpichnikovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Ekaterina N LyukmanovaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Alexander A VassilevskiShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Zakhar O ShenkarevShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Institute of Bioorganic Chemistry · RUInternational Tomography Center · RUMoscow Institute of Physics and Technology · RUUniversity College London · GBMRC Prion Unit · GBNational Research University Higher School of Economics · RUNovosibirsk Institute of Organic Chemistry · RU

Funding

Medical Research Council G0400136Medical Research Council G0400627Medical Research Council G0600368Medical Research Council G0601440Medical Research Council G0802158Medical Research Council G0900613Medical Research Council G116/147Medical Research Council G9805989Medical Research Council MR/M006948/1Wellcome Trust 209807/Z/17/ZWellcome Trust 212285/Z/18/Z
6 · The paper itself

Abstract

Voltage-gated sodium (Na

Indexed as

cell-free expressionchannelopathiescombinatorial selective labelinggating modifierligand-receptor interactionsNMR spectroscopysodium channel

Identifiers

PMID31555136
PMCPMC6737007
OpenAlexW2965897054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.