Evidence map›Paper›PMID 31555132›Full record

ArticleFrontiers in pharmacology2019

The Concentration of Memantine in the Cerebrospinal Fluid of Alzheimer's Disease Patients and Its Consequence to Oxidative Stress Biomarkers.

Martin Valis, David Herman, Nela Vanova, Jiri Masopust, Oldrich Vysata, Jakub Hort, Zbysek Pavelek, Blanka Klimova, Kamil Kuca, Jan Misik and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Martin ValisDepartment of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czechia.
David HermanBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czechia.
Nela VanovaDepartment of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense in Brno, Hradec Kralove, Czechia.
Jiri MasopustDepartment of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czechia.
Oldrich VysataDepartment of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czechia.
Jakub HortDepartment of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
Zbysek PavelekDepartment of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czechia.
Blanka KlimovaDepartment of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czechia.
Kamil KucaBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czechia.
Jan MisikBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czechia.
Jana Zdarova KarasovaBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czechia.
Charles University · CZUniversity Hospital Hradec Králové · CZUniversity of Defence · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memantine is a noncompetitive

Indexed as

Alzheimer’s diseasebiomarkerscerebrospinal fluid concentrationsclinical studymemantineoxidative stress

Identifiers

PMID31555132
PMCPMC6722429
OpenAlexW2963497689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.