Evidence map›Paper›PMID 31555097›Full record

ArticleFrontiers in cellular neuroscience2019

Cortical Plasticity Induced by Anodal Transcranial Pulsed Current Stimulation Investigated by Combining Two-Photon Imaging and Electrophysiological Recording.

Zengguang Ma, Xiaolang Du, Feifei Wang, Ran Ding, Yuanyuan Li, Aili Liu, Liangpeng Wei, Shaowei Hou, Feng Chen, Qi Hu and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
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  6. Review
  7. Article
  8. Effect of Transcranial Pulsed Current Stimulation on Fatigue Delay after Medium-Intensity Training.International journal of environmental research and public health · 2022
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Zengguang MaLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Xiaolang DuDepartment of Pharmacy, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Feifei WangLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Ran DingDepartment of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Yuanyuan LiLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Aili LiuLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Liangpeng WeiLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Shaowei HouLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Feng ChenLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Qi HuLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Cunle GuoLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Qingyan JiaoLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Shujing LiuLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Bei FangLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Hui ShenLaboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.
Tianjin Medical University · CNTianjin Medical University Cancer Institute and Hospital · CNTianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anodal-transcranial pulsed current stimulation (a-tPCS) has been used in human studies to modulate cortical excitability or improve behavioral performance in recent years. Multiple studies show crucial roles of astrocytes in cortical plasticity. The calcium activity in astrocytes could regulate synaptic transmission and synaptic plasticity. Whether the astrocytic activity is involved in a-tPCS-induced cortical plasticity is presently unknown. The purpose of this study is to investigate the calcium responses in neurons and astrocytes evoked by a-tPCS with different current intensities, and thereby provides some indication of the mechanisms underlying a-tPCS-induced cortical plasticity. Two-photon calcium imaging was used to record the calcium responses of neurons and astrocytes in mouse somatosensory cortex. Local field potential (LFP) evoked by sensory stimulation was used to assess the effects of a-tPCS on plasticity. We found that long-duration a-tPCS with high-intensity current could evoke large-amplitude calcium responses in both neurons and astrocytes, whereas long-duration a-tPCS with low-intensity current evoked large-amplitude calcium responses only in astrocytes. The astrocytic Ca

Indexed as

anodal transcranial pulsed current stimulationastrocytecortical plasticityelectrophysiological recordingneurontwo-photon calcium imaging

Identifiers

PMID31555097
PMCPMC6727068
OpenAlexW2969453966

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.