ArticleNature communications2019
Photoredox-catalyzed oxo-amination of aryl cyclopropanes.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The trial behind it
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Who cites it
17 citing papers in PubMed, 104 citations in OpenAlex.
- Photoredox-Neutral Platform for Direct Decarboxylative CyclopropanationACS catalysis · 2026Article
- Photocatalytic construction ofChemical science · 2026Article
- Desilylative allylation of 3,3-borylsilylpropene under metallaphotoredox catalysis.Nature communications · 2026Article
- Gamma Irradiation-Induced Changes in Microstructure of Cyclic Olefin Copolymer (COC) Revealed by NMR and SAXS Characterization.Polymers · 2025Article
- Concise Synthesis of Optically Active Cyclopropane β-Amino Acid Derivatives via Olefination of Cyclopropanone Surrogates.Organic letters · 2025Article
- Photocatalytic 1,3-oxyheteroarylation of aryl cyclopropanes with azineChemical science · 2024Article
- Selective monodeuteration enabled by bisphosphonium catalyzed ring opening processes.Nature communications · 2024Article
- Visible light-mediated organocatalyzed 1,3-aminoacylation of cyclopropane employing N-benzoyl saccharin as bifunctional reagent.Nature communications · 2024Article
- Photocatalytic (3 + 2) dipolar cycloadditions of aziridines driven by visible-light.Chemical science · 2023Article
- A copper-catalyzed four-component reaction of arylcyclopropanes, nitriles, carboxylic acids andChemical science · 2022Article
- Substrate-controlled C-H or C-C alkynylation of cyclopropanes: generation of aryl radical cations by direct light activation of hypervalent iodine reagents.Chemical science · 2022Article
- Photoredox-catalyzed C-C bond cleavage of cyclopropanes for the formation of C(spNature communications · 2022Article
- Recent advances in visible light-induced C(Nature reviews. Chemistry · 2022Article
- Cooperative NHC/Photoredox Catalyzed Ring-Opening of Aryl Cyclopropanes to 1-Aroyloxylated-3-Acylated Alkanes.Angewandte Chemie (International ed. in English) · 2021Article
- Electrocatalytic Activation of Donor-Acceptor Cyclopropanes and Cyclobutanes: An Alternative C(spAngewandte Chemie (International ed. in English) · 2021Article
- Electrochemical C-C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules.Nature communications · 2021Article
- Ring-opening 1,3-arylboration of arylcyclopropanes mediated by BClRSC advances · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyclopropanes represent a class of versatile building blocks in modern organic synthesis. While the release of ring strain offers a thermodynamic driving force, the control of selectivity for C-C bond cleavage and the subsequent regiochemistry of the functionalization remains difficult, especially for unactivated cyclopropanes. Here we report a photoredox-coupled ring-opening oxo-amination of electronically unbiased cyclopropanes, which enables the expedient construction of a host of structurally diverse β-amino ketone derivatives. Through one electron oxidation, the relatively inert aryl cyclopropanes are readily converted into reactive radical cation intermediates, which in turn participate in the ensuing ring-opening functionalizations. Based on mechanistic studies, the present oxo-amination is proposed to proceed through an S
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.