Evidence map›Paper›PMID 31554675›Full record

ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2020

Advances in stable isotope tracer methodology part 1: hepatic metabolism via isotopomer analysis and postprandial lipolysis modeling.

Cecilia Diniz Behn, Eunsook S Jin, Kate Bubar, Craig Malloy, Elizabeth J Parks, Melanie Cree-Green

Open access · greenAbstract read
In one paragraph

Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Cecilia Diniz BehnApplied Mathematics and Statistics, Colorado School of Mines, Golden, Colorado, USA.
Eunsook S JinAdvanced Imaging Research Center, UT Southwestern Medical, Dallas, Texas, USA.
Kate BubarApplied Mathematics and Statistics, Colorado School of Mines, Golden, Colorado, USA.
Craig MalloyAdvanced Imaging Research Center, UT Southwestern Medical, Dallas, Texas, USA.
Elizabeth J ParksDepartment of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, USA.
Melanie Cree-GreenDivision of Endocrinology, Department of Pediatrics, University of Colorado Anschutz School of Medicine, Aurora, Colorado, USA.ORCID 0000-0003-1593-1695
Advanced Imaging Research (United States) · USColorado School of Mines · USChildren's Hospital Colorado · USUniversity of Missouri · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI KHEMTONG, CHALERMCHAI · 2012 to 2021
$10.9M
UCHSC: Building Interdisciplinary Research Careers in Women's HealthK12HD057022 · NICHD · UNIVERSITY OF COLORADO DENVER · PI REGENSTEINER, JUDITH G., SANTORO, NANETTE F. · 2007 to 2023
$8.5M
13C asymmetry in blood glucose as a marker for oxidative stress in liverR01DK099289 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI JIN, EUNSOOK · 2014 to 2017
$1.1M
Influence of peripheral insulin resistance and hepatic lipogenesis on liver fat in obese PCOS girlsK23DK107871 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CREE, MELANIE G · 2015 to 2018
$743k
NCATS NIH HHS UL1 TR002535NIBIB NIH HHS P41 EB015908NICHD NIH HHS K12 HD057022NIDDK NIH HHS K23 DK107871NIDDK NIH HHS R01 DK099289
6 · The paper itself

Abstract

Stable isotope tracers have been used to gain an understanding of integrative animal and human physiology. More commonly studied organ systems include hepatic glucose metabolism, lipolysis from adipose tissue, and whole body protein metabolism. Recent improvements in isotope methodology have included the use of novel physiologic methods/models and mathematical modeling of data during different physiologic states. Here we review some of the latest advancements in this field and highlight future research needs. First we discuss the use of an oral [U-

Indexed as

IsotopesAdolescentChildFemaleGlucoseGlucose Tolerance TestGlycerolHumansLipolysisLiverModels, BiologicalObesityYoung AdultGlucoseGlycerolIsotopesadipose tissueliverresearch design

Identifiers

PMID31554675
PMCPMC7372575
OpenAlexW2976908812

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.