Evidence map›Paper›PMID 31554661›Full record

ArticleThe Journal of biological chemistry2019

Mitochondrial amidoxime-reducing component 2 (MARC2) has a significant role in

Sophia Rixen, Antje Havemeyer, Anita Tyl-Bielicka, Kazimiera Pysniak, Marta Gajewska, Maria Kulecka, Jerzy Ostrowski, Michal Mikula, Bernd Clement

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Loss of Mtarc1 Protects Against Steatotic Liver Disease in Mice.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. The History of mARC.Molecules (Basel, Switzerland) · 2023
    Review
  12. Hepatocyte mARC1 promotes fatty liver disease.JHEP reports : innovation in hepatology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sophia RixenDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian Albrechts University, 24118 Kiel, Germany.
Antje HavemeyerDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian Albrechts University, 24118 Kiel, Germany.
Anita Tyl-BielickaDepartment of Genetics, Maria Sklodowska-Curie Institute, Cancer Center, 02-781 Warsaw, Poland.
Kazimiera PysniakDepartment of Genetics, Maria Sklodowska-Curie Institute, Cancer Center, 02-781 Warsaw, Poland.ORCID 0000-0001-6461-2768
Marta GajewskaDepartment of Genetics, Maria Sklodowska-Curie Institute, Cancer Center, 02-781 Warsaw, Poland.
Maria KuleckaDepartment of Gastroenterology, Hepatology, and Clinical Oncology, Centre of Postgraduate Medical Education, 02-781 Warsaw, Poland.
Jerzy OstrowskiDepartment of Genetics, Maria Sklodowska-Curie Institute, Cancer Center, 02-781 Warsaw, Poland.
Michal MikulaDepartment of Genetics, Maria Sklodowska-Curie Institute, Cancer Center, 02-781 Warsaw, Poland mikula.michal@coi.pl.ORCID 0000-0003-3447-7328
Bernd ClementDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian Albrechts University, 24118 Kiel, Germany bclement@pharmazie.uni-kiel.de.
The Maria Sklodowska-Curie National Research Institute of Oncology · PLChristian-Albrechts-Universität zu Kiel · DEPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mitochondrial amidoxime-reducing component (MARC) is a mammalian molybdenum-containing enzyme. All annotated mammalian genomes harbor two MARC genes,

Indexed as

Energy MetabolismAnimalsDiet, High-FatFemaleMiceMice, Inbred C57BLMice, KnockoutMitochondrial ProteinsObesityOxidation-ReductionMitochondrial ProteinsMtarc2 protein, mousedrug metabolismenergy metabolismenzyme catalysisgene KOlipid metabolismmitochondrial amideoxime-reducing component (mARC)molybdenumN reductiontransgenic micexenobiotic metabolism

Identifiers

PMID31554661
PMCPMC6873197
OpenAlexW2975318158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.