ReviewDeutsches Arzteblatt international2019
Benign Breast Disease in Women.
Review in Deutsches Arzteblatt international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06494865 (" Role of Diffusion Weighted Image in the Diagnosis and Follow up of Breast Cancer"), which is not on this map. Cited by 72 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
" Role of Diffusion Weighted Image in the Diagnosis and Follow up of Breast Cancer"
Who cites it
72 citing papers in PubMed.
- Artificial Intelligence for Diagnostic and Prognostic Support in Breast Cancer: A Literature Overview.Cancers · 2026Review
- Clinical observation of ultrasound-guided microwave ablation for 1717 benign breast lesions: a multicenter study.Insights into imaging · 2026Article
- Retrospective Cohort Study: Extracting Coexisting Background Breast-Lesion Features from Stage I-III Invasive Breast Cancer.Cancers · 2026Article
- The role of preoperative lymphoscintigraphy in sentinel lymph node identification among patients with breast cancer: a retrospective study.Journal of medicine and life · 2026Article
- The Complex Path from Mammary Ductal Hyperplasia to Breast Cancer: Elevated Malignancy Risk in Atypical Forms.Biomedicines · 2026Review
- Article
- Metabolic syndrome is an independent correlate of breast nodules: a retrospective case-control study.Gland surgery · 2026Article
- Breast assessment using next generation handheld ultrasound device based on silicon chips: a pilot study in senology.Archives of gynecology and obstetrics · 2026Article
- Melatonin Supplementation Improves Pain, Sleep Quality, and Total Plasma Antioxidant Capacity in Women with Fibrocystic Breast Disease: A Randomized, Double-blind, Placebo-controlled Trial.Journal of research in pharmacy practice · 2026Article
- Misleading Presentation of Multilesional Benign Pathologies in the Breast: A Diagnostic Challenge.Cureus · 2026Article
- Integrating Ultrasound and DCE-MRI Improves Accuracy in Differentiating Breast Adenosis from Carcinoma.Breast cancer (Dove Medical Press) · 2026Article
- Epidemiology, early detection, and management of breast cancer in China: A comprehensive review.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025Article
- Unraveling breast cancer risk with a focus on menopausal status: a large case-control study.Cancer causes & control : CCC · 2025Article
- Impact of Prior Mammograms on Radiologists and Radiographers' Detection of Different Breast Cancer Lesion Types.Journal of medical radiation sciences · 2025Article
- Mammary Gland Microbiota in Benign Breast Diseases.International journal of molecular sciences · 2025Review
- Comparative Outcomes of Different Surgical Approaches for Non-Lactational Mastitis With Posterior and Non-Posterior Space Abscesses: A Retrospective Cohort Study.Immunity, inflammation and disease · 2025Article
- Deep Phenotyping of Pathology-Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients.Clinical genetics · 2025Article
- Advances in biomonitoring technologies for women's health.Nature communications · 2025Review
- Article
- A comparative analysis of the clinical effect of multiple treatments for benign breast tumors.The Journal of international medical research · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost clinical breast changes in women are benign; in only 3% to 6% of cases are they due to breast cancer. How- ever, there is a lack of up-to-date, evidence-based treatment recommendations for the various benign differential diagnoses.
methodsSelective literature search of PubMed from 1985 to May 2019, including current national (AWMF, Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften [Association of Scientific Medical Societies in Germany]) and inter- national guidelines.
resultsMastalgia and fibrocystic changes are common (around 50% of all women over the age of 30). Fibroadenomas occur in 25% of women; they are the most common benign tumors of the breast and do not require treatment. With most benign breast changes the risk of dedifferentiation is very low. However, it is important in the differential diagnosis to distinguish between such benign changes and breast cancer or changes that carry a risk of malignancy. Complex cysts, for example, carry a risk of malig- nancy of 23% to 31%, papillary lesions 16% , and radial scars 7%. Where there is doubt, histological confirmation should be sought by means of percutaneous biopsy.
conclusionBenign breast changes can be definitively distinguished from malignant lesions through the selective use of avail- able diagnostic investigations and interdisciplinary collaboration. When lesions of uncertain malignant potential are found (B3 in the biopsy classification), complete excision is indicated. Prospective studies on the early diagnosis of breast cancer in lesions carrying a risk of malignancy are desirable.
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