ReviewDeutsches Arzteblatt international2019
Health Risks and Interventions in Exertional Heat Stress.
Review in Deutsches Arzteblatt international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Epidemiology of Exertional Heat Illness in the Military: A Systematic Review of Observational Studies.International journal of environmental research and public health · 2020Pooled it
- Review
- Heat- and Cold-Associated Mortality in Germany, 2000-2023.Deutsches Arzteblatt international · 2026Observational
- Heat Stress and Kidney Injury: A Growing Concern Amidst Climate Change.Kidney medicine · 2026Review
- Brief extreme passive heat exposure leads to elevated biomarkers of systemic inflammation and acute kidney injury in older vs young adults.European journal of applied physiology · 2025Article
- Evaporative microclimate interval cooling reduces heat stress in thermal insulating protective clothing.Journal of occupational medicine and toxicology (London, England) · 2025Article
- Wearable device-based interventions in heat-exposed outdoor workers - a scoping review and an explanatory intervention model.BMC public health · 2025Article
- The Singapore Physical Activity Readiness Questionnaire 2021 (SPARQ 2021)-Results of Public Feedback.Healthcare (Basel, Switzerland) · 2025Article
- High indoor temperatures increase reporting of acute symptoms: finding mitigating solutions for the climate-vulnerable of Bangladesh.BMC public health · 2025Article
- From inequalities to vulnerability paradoxes: juxtaposing older adults' heat mortality risk and heat experiences.Environmental health : a global access science source · 2025Article
- The molecular signature of heat stress in sweat reveals non-invasive biomarker candidates for health monitoring.Communications biology · 2025Article
- The Heat Is On: Climate Change Implications for Pregnant Women with Sickle Cell Disease.Women's health reports (New Rochelle, N.Y.) · 2025Review
- Cold-water immersion alleviates intestinal damage induced by exertional heat stroke via modulation of gut microbiota in rats.Frontiers in microbiomes · 2025Article
- BHBA attenuates endoplasmic reticulum stress-dependent neuroinflammation via the gut-brain axis in a mouse model of heat stress.CNS neuroscience & therapeutics · 2024Article
- [Pathophysiology and management of heat illness].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024Review
- Sex-Specific Association of Ambient Temperature With Urine Biomarkers in Southwest Coastal Bangladesh.Kidney international reports · 2024Article
- Modeling thermoregulatory responses during high-intensity exercise in warm environments.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Heat exposure as a cause of injury and illness in mine industry workers.Annals of work exposures and health · 2024Article
- From Health-in-All-Policies to Climate-in-All-Policies: Using the Synergies between Health Promotion and Climate Protection to Take Action.International journal of environmental research and public health · 2024Review
- Associations Between Air Temperature and Daily Varicella Cases - Jinan City, Shandong Province, China, 2019-2021.China CDC weekly · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith climate change, heat waves are expected to become more frequent in the near future. Already, on average more than 25 000 "heat deaths" are estimated to occur in Europe every year. However, heat stress and heat illnesses arise not just when ambient temperatures are high. Physical exertion increases heat production within the organism many times over; if not enough heat is lost, there is a risk of exertional heat stress. This review article discusses contributing factors, at-risk groups, and the diagnosis and treatment of heat illnesses.
methodsA selective literature search was carried out on PubMed. Current guidelines and expert recommendations were also included.
resultsApart from muscular heat production (>70% of converted energy), there are other factors that singly or in combination can give rise to heat stress: clothing, climate/acclimatization, and individual factors. Through its insulating properties, clothing reduces the evaporation of sweat (the most effective physiological cooling mechanism). A sudden heat wave, or changing the climate zone (as with air travel), increases the risk of a heat-related health event. Overweight, low fitness level, acute infections, illness, dehydration, and other factors also reduce heat tolerance. In addition to children, older people are particularly at risk because of their reduced physiological adaptability, (multi-)morbidity, and intake of prescription drugs. A heat illness can progress suddenly to life-threatening heat stroke. Successful treatment depends on rapid diagnosis and cooling the body down as quickly as possible. The aim is to reduce core body temperature to <40 °C within 30 minutes.
conclusionImmediately effective cooling interventions are the only causal treatment for heat stroke. Time once lost cannot be made up. Prevention (acclimatization, reduced exposure, etc.) and terminating the heat stress in good time (e.g., stopping work) are better than any cure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.