Evidence map›Paper›PMID 31554515›Full record

ArticleBMC research notes2019

Thrombocytopenia according to antiretroviral drug combinations, viremia and CD4 lymphocytes among HIV-infected patients in Cameroon: a snapshot from the City of Yaoundé.

Alex Durand Nka, Samuel Martin Sosso, Joseph Fokam, Yagai Bouba, Georges Teto, Rachel Simo Rachel, Aline Tiga, Junie Yimga, Elias Nchiwan Nukenine, Aubin Joseph Nanfack and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Alex Durand Nka"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon. nkaalexdurand@yahoo.fr.ORCID http://orcid.org/0000-0002-9358-8661
Samuel Martin Sosso"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Joseph Fokam"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon. josephfokam@gmail.com.
Yagai Bouba"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Georges Teto"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Rachel Simo Rachel"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Aline Tiga"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Junie Yimga"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Elias Nchiwan NukenineFaculty of Sciences, University of Ngaoundéré, Ngaoundéré, Cameroon.
Aubin Joseph Nanfack"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Désiré Takou"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Zélateur ArogaNgaoundéré Presbyterian Hospital, Ngaoundéré, Cameroon.
Vittorio Colizzi"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Alexis Ndjolo"Chantal BIYA" International Reference Centre for Research on HIV/AIDS Prevention and Management, (CIRCB), Yaoundé, Cameroon.
Centre International De Reference Chantal Biya · CMUniversité de Yaoundé I · CMUniversity of Ngaoundéré · CMUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThrombocytopenia is an abnormal decrease in blood platelets, which can affect the prognosis of people living with HIV (PLHIV). In order to assess the burden of this haematological disorder, we evaluated the frequency of thrombocytopenia according to antiretroviral drug combinations, viremia and the immune status of PLHIV.

resultsA cross-sectional and analytical study was conducted from June to November 2016 among 310 PLHIV at the "Chantal BIYA" International Reference Centre, Yaoundé, Cameroon. Overall rate of thrombocytopenia was 19.0% (59/310). The rate of thrombocytopenia was 64.6% (42/65) versus 6.9% (17/245) in ART-naïve versus ART-treated patients respectively, p < 0.0001. Following viral load, rate of thrombocytopenia was 15.8% (20/130) in those with undetectable viral load, and 34.1% (27/79) with viral loads > 3 log

Indexed as

AdolescentAdultAnti-Retroviral AgentsCameroonCD4 Lymphocyte CountChildChild, PreschoolCitiesCross-Sectional StudiesDrug CombinationsFemaleHIV-1HIV InfectionsHumansInfantInfant, NewbornAnti-Retroviral AgentsDrug CombinationsAntiretroviral triple therapyCameroonCD4HIVThrombocytopeniaViral load

Identifiers

PMID31554515
PMCPMC6761711
OpenAlexW2974944247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.