Evidence map›Paper›PMID 31554363›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2019

Late Effects of Breast Cancer Treatment and Outcome after Corrective Interventions.

Unni S Pillai, Smita Kayal, Sunu Cyriac, Yadav Nisha, Kadambari Dharanipragada, Sadish Kumar Kamalanathan, Dhanapathi Halanaik, Navin Kumar, Ponraj Madasamy, Dhanraju Krishnappa Muniswamy and 1 more

Open access · goldAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Mindfulness-based interventions for breast cancer patients in China across outcome domains: a systematic review and meta-analysis of the Chinese literature.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
  3. Trial
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  8. Evaluation of the thyroid and hypothyroid function after postoperative radiation therapy among breast cancer patients.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2024
    Article
  9. Article
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  12. The role of loco-regional treatment in long-term quality of life in de novo stage IV breast cancer patients: protocol MF07-01Q.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Unni S PillaiDepartment of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India. Email:drbiswajitdm@gmail.com
Smita KayalDepartment of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India. Email:drbiswajitdm@gmail.com
Sunu CyriacDepartment of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India. Email:drbiswajitdm@gmail.com
Yadav NishaDepartment of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India. Email:drbiswajitdm@gmail.com
Kadambari DharanipragadaDepartment of Surgery, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India.
Sadish Kumar KamalanathanDepartment of Endocrinology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India.
Dhanapathi HalanaikDepartment of Nuclear Medicine,Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India.
Navin KumarDepartment of Physiology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India.
Ponraj MadasamyDepartment of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India. Email:drbiswajitdm@gmail.com
Dhanraju Krishnappa MuniswamyDepartment of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India. Email:drbiswajitdm@gmail.com
Biswajit DubashiDepartment of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, India. Email:drbiswajitdm@gmail.com
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To study the late toxicities of treatment and its impact on Breast cancer survivors among Indian patients. Materials and Methods: Our study recruited 152 curatively treated non metastatic carcinoma breast patients. The baseline demographic details, disease related and treatment related information were collected. The late effects included breast cancer related lymphedema, shoulder dysfunction, treatment induced bone loss, hypothyroidism, cardiac dysfunction, and chemotherapy induced cognitive dysfunction and Quality of life. Results: The median age was 47 years (range 27 -72 years). The cumulative frequency of BCRL and shoulder dysfunction was 31.57% and 34.86% respectively. The improvement in BCRL with corrective intervention was not statistically significant. The BCRL was significantly associated with shoulder dysfunction. The frequency of loss of bone mineral density was 38.15%. There was statistically significant improvement in bone mineral density with interventions. The cumulative rate of hypothyroidism and cardiac dysfunction was 14.47 % and 2.17% respectively which improved after corrective therapy. We did not find any delayed cognitive dysfunction. There was improvement in global health, physical function, role function, fatigue, Nausea, vomiting, pain scores, insomnia, Loss of appetite, diarrhea and arm symptoms over time with intervention. Conclusion: Our study has shown that nearly half of the survivors were suffering from at least one of the late effects. The intervention helped in improving the loss of bone mineral density, hypothyroidism, cardiac dysfunction and quality of life in Breast cancer survivors.

Indexed as

Quality of LifeAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBreast Cancer LymphedemaBreast NeoplasmsCancer SurvivorsCognition DisordersCombined Modality TherapyFemaleFollow-Up StudiesHumansMastectomyMiddle AgedProspective StudiesRadiotherapybreast cancerLate effectsQuality of Life

Identifiers

PMID31554363
PMCPMC6976858
OpenAlexW2976453555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.