Evidence map›Paper›PMID 31554228›Full record

ArticleMicroorganisms2019

Monica Salamone, Aldo Nicosia, Giulio Ghersi, Marcello Tagliavia

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. High Proteolytic and Collagenolytic Activity in an EnvironmentalInternational journal of molecular sciences · 2025
    Article
  3. Camel milkFrontiers in nutrition · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Targeting Virulence Genes Expression inInternational journal of molecular sciences · 2022
    Article
  9. Frontiers in cellular and infection microbiology · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Monica SalamoneAbiel s.r.l, via del Mare 3, 91021 Campobello di Mazara (TP), Italy. m.salamone@abielbiotech.com.
Aldo NicosiaIRIB-CNR (Institute for Biomedical Research and Innovation-National Research Council), Via Ugo La Malfa 153, 90146 Palermo, Italy. aldo.nicosia@cnr.it.ORCID 0000-0002-1013-2862
Giulio GhersiAbiel s.r.l, via del Mare 3, 91021 Campobello di Mazara (TP), Italy. giulio.ghersi@unipa.it.ORCID 0000-0001-7250-9808
Marcello TagliaviaIRIB-CNR (Institute for Biomedical Research and Innovation-National Research Council), Via Ugo La Malfa 153, 90146 Palermo, Italy. marcello.tagliavia@cnr.it.ORCID 0000-0002-0960-2919
Institute for Biomedical Research and Innovation · ITUniversity of Palermo · IT

Funding

H2020 European Institute of Innovation and Technology 691128
6 · The paper itself

Abstract

Proteolytic enzymes are of great interest for biotechnological purposes, and their large-scale production, as well as the discovery of strains producing new molecules, is a relevant issue. Collagenases are employed for biomedical and pharmaceutical purposes. The high specificity of collagenase-based preparations toward the substrate strongly relies on the enzyme purity. However, the overall activity may depend on the cooperation with other proteases, the presence of which may be essential for the overall enzymatic activity, but potentially harmful for cells and tissues. Vibrios produce some of the most promising bacterial proteases (including collagenases), and their exo-proteome includes several enzymes with different substrate specificities, the production and relative abundances of which strongly depend on growth conditions. We evaluated the effects of different media compositions on the proteolytic exo-proteome of

Indexed as

collagenaseproteases productionproteolytic secretomeV. alginolyticusV. parahaemolyticus

Identifiers

PMID31554228
PMCPMC6843219
OpenAlexW2975702057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.