Evidence map›Paper›PMID 31554204›Full record

ArticleInternational journal of molecular sciences2019

Associations between Monocyte and T Cell Cytokine Profiles in Autism Spectrum Disorders: Effects of Dysregulated Innate Immune Responses on Adaptive Responses to Recall Antigens in a Subset of ASD Children.

Harumi Jyonouchi, Lee Geng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

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  16. CouldJournal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Harumi JyonouchiDepartment of Pediatrics, Saint Peter's University Hospital (SPUH), New Brunswick, NJ 08901, USA. hjyonouchi@saintpetersuh.com.
Lee GengDepartment of Pediatrics, Saint Peter's University Hospital (SPUH), New Brunswick, NJ 08901, USA. lgeng@saintpetersuh.com.
Rutgers, The State University of New Jersey · USSaint Peter's University Hospital · US

Funding

Jonty Foundation, St. Paul, MN 18JAN01The Governor's Council for Medical Research and Treatment of Autism, DHHS, NJ CAUT16APL007
6 · The paper itself

Abstract

Changes in monocyte cytokine production with toll like receptor (TLR) agonists in subjects with autism spectrum disorders (ASD) were best reflected by the IL-1β/IL-10 ratios in our previous research. The IL-1β/IL-10 based subgrouping (low, normal, and high) of ASD samples revealed marked differences in microRNA expression, and mitochondrial respiration. However, it is unknown whether the IL-1β/IL-10 ratio based subgrouping is associated with changes in T cell cytokine profiles or monocyte cytokine profiles with non-TLR agonists. In ASD (

Indexed as

Adaptive ImmunityAdolescentAdultAntigensAutism Spectrum DisorderBiomarkersChildChild, PreschoolCytokinesFemaleHumansImmunity, InnateImmunologic MemoryMaleMonocytesSeverity of Illness IndexAntigensBiomarkersCytokinesASDcytokinematernal immune activationmonocyteT cell cytokinetrained immunityβ-glucan

Identifiers

PMID31554204
PMCPMC6801811
OpenAlexW2976663473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.