Evidence map›Paper›PMID 31553873›Full record

ArticleJournal of medicinal chemistry2019

Anti-biofilm Agents against

Roman Sommer, Katharina Rox, Stefanie Wagner, Dirk Hauck, Sarah S Henrikus, Shelby Newsad, Tatjana Arnold, Thomas Ryckmans, Mark Brönstrup, Anne Imberty and 3 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Glyco-Nanogels for Modulating Pseudomonas aeruginosa Biofilm.Macromolecular rapid communications · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Anti-Biofilm Agents to OvercomePharmaceuticals (Basel, Switzerland) · 2025
    Review
  10. Article
  11. Article
  12. Insights onMicroorganisms · 2024
    Article
  13. Article
  14. Bioactive Compounds fromMolecules (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Inhibition and eradication ofRSC medicinal chemistry · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Roman SommerChemical Biology of Carbohydrates , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research , D-66123 Saarbrücken , Germany.
Katharina RoxDeutsches Zentrum für Infektionsforschung (DZIF) , Standort Hannover, D-38124 Braunschweig , Germany.
Stefanie WagnerChemical Biology of Carbohydrates , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research , D-66123 Saarbrücken , Germany.
Dirk HauckChemical Biology of Carbohydrates , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research , D-66123 Saarbrücken , Germany.
Sarah S HenrikusChemical Biology of Carbohydrates , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research , D-66123 Saarbrücken , Germany.
Shelby NewsadChemical Biology of Carbohydrates , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research , D-66123 Saarbrücken , Germany.
Tatjana ArnoldDeutsches Zentrum für Infektionsforschung (DZIF) , Standort Hannover, D-38124 Braunschweig , Germany.
Thomas RyckmansRoche Pharmaceutical Research and Early Development , Roche Innovation Center Basel , CH-4070 Basel , Switzerland.
Mark BrönstrupDeutsches Zentrum für Infektionsforschung (DZIF) , Standort Hannover, D-38124 Braunschweig , Germany.ORCID 0000-0002-8971-7045
Anne ImbertyUniv. Grenoble Alpes , CNRS, CERMAV , F-38000 Grenoble , France.
Annabelle VarrotUniv. Grenoble Alpes , CNRS, CERMAV , F-38000 Grenoble , France.ORCID 0000-0001-6667-8162
Rolf W HartmannDeutsches Zentrum für Infektionsforschung (DZIF) , Standort Hannover, D-38124 Braunschweig , Germany.ORCID 0000-0002-5871-5231
Alexander TitzChemical Biology of Carbohydrates , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research , D-66123 Saarbrücken , Germany.ORCID 0000-0001-7408-5084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilm formation is a key mechanism of antimicrobial resistance. We have recently reported two classes of orally bioavailable

Indexed as

AnimalsAnti-Bacterial AgentsBinding SitesBiofilmsCell LineCell SurvivalCrystallography, X-RayDrug DesignGlycosidesHumansLectinsMiceMicrosomes, LiverMolecular Dynamics SimulationPseudomonas aeruginosaStructure-Activity RelationshipAnti-Bacterial AgentsC-glycosideGlycosidesLecB protein, Pseudomonas aeruginosaLectinsSulfonamides

Identifiers

PMID31553873
PMCPMC6873108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.