ArticlePloS one2019
A usability study to improve a clinical decision support system for the prescription of antibiotic drugs.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Optimizing Clinical Decision Support System Functionality by Leveraging Specific Human-Computer Interaction Elements: Insights From a Systematic Review.JMIR human factors · 2025Pooled it
- Factors influencing the implementation of decision support systems for antibiotic prescription in hospitals: a systematic review.BMC medical informatics and decision making · 2023Pooled it
- Pooled it
- Comparing safety, performance and user perceptions of a patient-specific indication-based prescribing tool with current practice: a mixed methods randomised user testing study.BMJ quality & safety · 2025Trial
- A Mobile Health Salt Reduction Intervention for People With Hypertension: Results of a Feasibility Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- Enhancing quality of antimicrobial prescribing through 'Ask Eolas' (language model): a user-testing and simulation evaluation.npj antimicrobials and resistance · 2026Article
- Investigating the Feasibility, Usability, and Efficacy of a Mobile App to Reduce Anxiety and Depression in Families of Critical Care Cancer Patients: A Quasi-Experimental Pilot Study.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Evaluating the impact of an indication-based, patient-specific prescribing tool on prescribing errors in paediatrics: a non-randomised, before-and-after study.BMJ paediatrics open · 2025Article
- Usability Testing of Situation Awareness Clinical Decision Support in the Intensive Care Unit.Applied clinical informatics · 2024Article
- Physicians' Perspectives on AI in Clinical Decision Support Systems: Interview Study of the CURATE.AI Personalized Dose Optimization Platform.JMIR human factors · 2023Article
- A case-based reasoning system for neonatal survival and LOS prediction in neonatal intensive care units: a development and validation study.Scientific reports · 2023Article
- Usability of the IDDEAS prototype in child and adolescent mental health services: A qualitative study for clinical decision support system development.Frontiers in psychiatry · 2023Article
- The development and implementation of a guideline-based clinical decision support system to improve empirical antibiotic prescribing.BMC medical informatics and decision making · 2022Article
- A Web Interface for Antibiotic Prescription Recommendations in Primary Care: User-Centered Design Approach.Journal of medical Internet research · 2021Article
- User-centred design of a clinical decision support system for palliative care: Insights from healthcare professionals.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveA clinical decision support system (CDSS) for empirical antibiotic treatment has the potential to increase appropriate antibiotic use. Before using such a system on a broad scale, it needs to be tailored to the users preferred way of working. We have developed a CDSS for empirical antibiotic treatment in hospitalized adult patients. Here we determined in a usability study if the developed CDSS needed changes.
methodsFour prespecified patient cases, based on real life clinical scenarios, were evaluated by 8 medical residents in the study. The "think-aloud" method was used, and sessions were recorded and analyzed afterwards. Usability was assessed by 3 evaluators using an augmented classification scheme, which combines the User Action Framework with severity rating of the usability problems and the assessment of the potential impact of these problems on the final task outcomes.
resultsIn total 51 usability problems were identified, which could be grouped into 29 different categories. Most (n = 17/29) of the usability problems were cosmetic problems or minor problems. Eighteen (out of 29) of the usability categories could have an ordering error as a result. Classification of the problems showed that some of the problems would get a low priority based on their severity rating, but got a high priority for their impact on the task outcome. This effectively provided information to prioritize system redesign efforts.
conclusionUsability studies improve lay-out and functionality of a CDSS for empirical antibiotic treatment, even after development by a multidisciplinary system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.