ArticleJournal of neurophysiology2019
Altered functional interactions between neurons in primary visual cortex of macaque monkeys with experimental amblyopia.
Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Efficacy of binocular vision training and Fresnel press-on prism on children with esotropia and amblyopia.International ophthalmology · 2023Trial
- Comparative Effects of Monocular and Stereopsis Training on Visual Acuity and Stereoacuity in Children With Amblyopia.Investigative ophthalmology & visual science · 2026Article
- Neurophysiological basis for visual distortions in amblyopia.Frontiers in neuroscience · 2026Review
- Refractive factors affecting the persistence of anisometropia in preschool-aged children.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Monocular Contrast Sensitivity Visual Perceptual Learning Rebalances Adult Amblyopes' Two Eyes.Investigative ophthalmology & visual science · 2025Article
- Reduced interocular suppression after inverse patching in anisometropic amblyopia.Frontiers in neuroscience · 2023Article
- Rethinking amblyopia 2020.Vision research · 2020Review
- Leveraging neural plasticity for the treatment of amblyopia.Survey of ophthalmologyReview
- Comparison of binocular visual function among patients with different types of anisometropia.Advances in ophthalmology practice and researchArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Amblyopia, a disorder in which vision through one of the eyes is degraded, arises because of defective processing of information by the visual system. Amblyopia often develops in humans after early misalignment of the eyes (strabismus) and can be simulated in macaque monkeys by artificially inducing strabismus. In such amblyopic animals, single-unit responses in primary visual cortex (V1) are appreciably reduced when evoked by the amblyopic eye compared with the other (fellow) eye. However, this degradation in single V1 neuron responsivity is not commensurate with the marked losses in visual sensitivity and resolution measured behaviorally. Here we explored the idea that changes in patterns of coordinated activity across populations of V1 neurons may contribute to degraded visual representations in amblyopia, potentially making it more difficult to read out evoked activity to support perceptual decisions. We studied the visually evoked activity of V1 neuronal populations in three macaques (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.