Evidence map›Paper›PMID 31553667›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2019

Unfolding the Story of Proteoglycan Accumulation in Thoracic Aortic Aneurysm and Dissection.

Ying H Shen, Hong S Lu, Scott A LeMaire, Alan Daugherty

Abstract readEditorialComment
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
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  5. Review
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  9. Review
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  14. Differential propensity of dissection along the aorta.Biomechanics and modeling in mechanobiology · 2021
    Article
  15. Article
  16. Aortic Aneurysms and Dissections Series.Arteriosclerosis, thrombosis, and vascular biology · 2020
    Review
4 · The record

Corrections and comments

  • Comment on
    2019
5 · Who and what money

Authors and funding

4 authors.

Ying H ShenFrom the Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston (Y.H.S., S.A.L.).
Hong S LuSaha Cardiovascular Research Center (H.S.L., A.D.), University of Kentucky, Lexington.
Scott A LeMaireFrom the Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston (Y.H.S., S.A.L.).
Alan DaughertySaha Cardiovascular Research Center (H.S.L., A.D.), University of Kentucky, Lexington.

Funding

Adventitial-medial interactions in thoracic aortic diseasesR01HL133723 · NHLBI · UNIVERSITY OF KENTUCKY · PI DAUGHERTY, ALAN · 2016 to 2019
$2.9M
Atherosclerosis Mechanisms: Angiotensin II production and actionR01HL139748 · NHLBI · UNIVERSITY OF KENTUCKY · PI DAUGHERTY, ALAN, LU, HONG SHEN · 2018 to 2021
$2.0M
Targeting ER Stress To Treat Aortic Aneurysms and DissectionsR01HL131980 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LEMAIRE, SCOTT A, SHEN, YING H · 2016 to 2019
$1.7M
Targeting the Inflammasome to Prevent Thoracic Aortic Aneurysms and DissectionsR01HL127111 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LEMAIRE, SCOTT A · 2016 to 2019
$1.6M
Mitochondrial Damage-Induced Necroptotic Cell Death in SporadicAscending Thoracic Aortic Aneurysms and DissectionsR01HL143359 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LEMAIRE, SCOTT A, SHEN, YING H · 2018 to 2021
$1.6M
Targeting the Inflammasome to Prevent Thoracic Aortic Aneurysms and DissectionsR56HL127111 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LEMAIRE, SCOTT A · 2015 to 2015
$396k
NHLBI NIH HHS R01 HL127111NHLBI NIH HHS R01 HL131980NHLBI NIH HHS R01 HL133723NHLBI NIH HHS R01 HL139748NHLBI NIH HHS R01 HL143359NHLBI NIH HHS R56 HL127111
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aortic Aneurysm, ThoracicAortic DissectionADAMTS5 ProteinAggrecansAnimalsAortaMiceProteoglycansADAMTS5 ProteinAdamts5 protein, mouseAggrecansProteoglycansADAMTS proteasesaggrecansaortic aneurysmaortic dissectionEditorialextracellular matrixproteoglycans

Identifiers

PMID31553667
PMCPMC6764585

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.