Evidence map›Paper›PMID 31553655›Full record

ArticleEnvironmental health perspectives2019

The Role of Humidity in Associations of High Temperature with Mortality: A Multicountry, Multicity Study.

Ben Armstrong, Francesco Sera, Ana Maria Vicedo-Cabrera, Rosana Abrutzky, Daniel Oudin Åström, Michelle L Bell, Bing-Yu Chen, Micheline de Sousa Zanotti Stagliorio Coelho, Patricia Matus Correa, Tran Ngoc Dang and 30 more

Erratum issuedAbstract read
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Article in Environmental health perspectives, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 85 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Building the model: a review of input structures in extreme temperature-health.Environmental health : a global access science source · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. [Environmental relative humidity, frailty, and risk of incident stroke among middle-aged and older adults in China: A prospective cohort study].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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  17. Ten new insights in climate science 2024.One earth (Cambridge, Mass.) · 2025
    Review
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

40 authors.

Ben ArmstrongDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Francesco SeraDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Ana Maria Vicedo-CabreraDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Rosana AbrutzkyUniversidad de Buenos Aires, Facultad de Ciencias Sociales, Instituto de Investigaciones Gino Germani, Buenos Aires, Argentina.
Daniel Oudin ÅströmSection of Sustainable Health, Department of Occupational and Environmental Medicine, Umeå University, Umeå, Sweden.
Michelle L BellSchool of Forestry and Environmental Studies, Yale University, New Haven, Connecticut, USA.
Bing-Yu ChenNational Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.
Micheline de Sousa Zanotti Stagliorio CoelhoInstitute of Advanced Studies, University of São Paulo, São Paulo, Brazil.
Patricia Matus CorreaDepartment of Public Health, Universidad de los Andes, Santiago, Chile.
Tran Ngoc DangInstitute of Research and Development, Duy Tan University, Da Nang, Vietnam.
Magali Hurtado DiazDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Do Van DungDepartment of Environmental Health, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Bertil ForsbergDepartment of Public Health and Clinical Medicine, Umeå University, Sweden.
Patrick GoodmanTechnological University Dublin (TU Dublin), Dublin, Ireland.
Yue-Liang Leon GuoNational Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.
Yuming GuoDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Masahiro HashizumeDepartment of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Yasushi HondaFaculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.
Ene IndermitteDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Carmen ÍñiguezDepartment of Statistics and Computational Research, University of València, València, Spain.
Haidong KanDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai, China.
Ho KimGraduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Jan KyselýInstitute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Eric LavigneSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Paola MichelozziDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Hans OrruDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Nicolás Valdés OrtegaDepartment of Public Health, Universidad de los Andes, Santiago, Chile.
Mathilde PascalSanté Publique France, Department of Environmental Health, French National Public Health Agency, Saint Maurice, France.
Martina S RagettliSwiss Tropical and Public Health Institute, Basel, Switzerland.
Paulo Hilario Nascimento SaldivaInstitute of Advanced Studies, University of São Paulo, São Paulo, Brazil.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Matteo ScortichiniAir Health Science Division, Health Canada, Ottawa, Canada.
Xerxes SeposoDepartment of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan.
Aurelio TobiasInstitute of Environmental Assessment and Water Research (IDAEA), Spanish Council for Scientific Research (CSIC), Barcelona, Spain.
Shilu TongShanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Aleš UrbanInstitute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
César De la Cruz ValenciaDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Ariana ZekaInstitute for the Environment, Brunel University London, London, UK.
Antonio GasparriniDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.

Funding

Environmental Health Disparities in an Older PopulationR01MD012769 · NIMHD · YALE UNIVERSITY · PI BELL, MICHELLE L · 2017 to 2021
$3.9M
Medical Research Council MR/M022625/1Medical Research Council MR/R013349/1NIMHD NIH HHS R01 MD012769
6 · The paper itself

Abstract

backgroundThere is strong experimental evidence that physiologic stress from high temperatures is greater if humidity is higher. However, heat indices developed to allow for this have not consistently predicted mortality better than dry-bulb temperature.

objectivesWe aimed to clarify the potential contribution of humidity an addition to temperature in predicting daily mortality in summer by using a large multicountry dataset.

methodsIn 445 cities in 24 countries, we fit a time-series regression model for summer mortality with a distributed lag nonlinear model (DLNM) for temperature (up to lag 3) and supplemented this with a range of terms for relative humidity (RH) and its interaction with temperature. City-specific associations were summarized using meta-analytic techniques.

resultsAdding a linear term for RH to the temperature term improved fit slightly, with an increase of 23% in RH (the 99th percentile anomaly) associated with a 1.1% [95% confidence interval (CI): 0.8, 1.3] decrease in mortality. Allowing curvature in the RH term or adding terms for interaction of RH with temperature did not improve the model fit. The humidity-related decreased risk was made up of a positive coefficient at lag 0 outweighed by negative coefficients at lags of 1-3 d. Key results were broadly robust to small model changes and replacing RH with absolute measures of humidity. Replacing temperature with apparent temperature, a metric combining humidity and temperature, reduced goodness of fit slightly. DISCUSSION: The absence of a positive association of humidity with mortality in summer in this large multinational study is counter to expectations from physiologic studies, though consistent with previous epidemiologic studies finding little evidence for improved prediction by heat indices. The result that there was a small negative average association of humidity with mortality should be interpreted cautiously; the lag structure has unclear interpretation and suggests the need for future work to clarify. https://doi.org/10.1289/EHP5430.

Indexed as

Hot TemperatureHumidityCitiesEnvironmental ExposureHumansMortalityNonlinear DynamicsSeasons

Identifiers

PMID31553655
PMCPMC6792461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.