ArticleAmerican journal of physiology. Lung cellular and molecular physiology2020
MicroRNA-mediated downregulation of K
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In one paragraph
Article in American journal of physiology. Lung cellular and molecular physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Potassium channels in vascular smooth muscle cells.Physiological reviews · 2026Review
- BK channels are indispensable for endothelial function in small pulmonary arteries.Cell communication and signaling : CCS · 2025Article
- miRNAs in Pulmonary Hypertension: Mechanistic Insights and Therapeutic Potential.Biomedicines · 2025Review
- Pulmonary Circulation Under Pressure: Pathophysiological and Therapeutic Implications of BK Channel.Cardiovascular drugs and therapy · 2025Review
- The Role of miR-138 in Cardiovascular Diseases.BioMed research international · 2025Review
- Up-regulated expression of two-pore domain KFrontiers in cardiovascular medicine · 2024Article
- Impact of aging on vascular ion channels: perspectives and knowledge gaps across major organ systems.American journal of physiology. Heart and circulatory physiology · 2023Review
- Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension.Frontiers in cell and developmental biology · 2023Review
- MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents.Molecular therapy. Nucleic acids · 2022Article
- Role of Ion Channel Remodeling in Endothelial Dysfunction Induced by Pulmonary Arterial Hypertension.Biomolecules · 2022Review
- Expression of the microRNA-30 family in pulmonary arterial hypertension and the role of microRNA-30d-5p in the regulation of pulmonary arterial smooth muscle cell toxicity and apoptosis.Experimental and therapeutic medicine · 2022Article
- Revisiting the Large-Conductance Calcium-Activated Potassium (BKCa) Channels in the Pulmonary Circulation.Biomolecules · 2021Review
- Ion channels as convergence points in the pathology of pulmonary arterial hypertension.Biochemical Society transactions · 2021Review
- MicroRNA-210 Mediates Hypoxia-Induced Repression of Spontaneous Transient Outward Currents in Sheep Uterine Arteries During Gestation.Hypertension (Dallas, Tex. : 1979) · 2021Article
- MicroRNA‑153 attenuates hypoxia‑induced excessive proliferation and migration of pulmonary arterial smooth muscle cells by targeting ROCK1 and NFATc3.Molecular medicine reports · 2021Article
- mTOR Signaling in Pulmonary Vascular Disease: Pathogenic Role and Therapeutic Target.International journal of molecular sciences · 2021Review
- Non-Coding RNA Networks in Pulmonary Hypertension.Frontiers in genetics · 2021Review
- In vivo miR-138-5p inhibition alleviates monocrotaline-induced pulmonary hypertension and normalizes pulmonary KCNK3 and SLC45A3 expression.Respiratory research · 2020Article
- The Role of MicroRNA in the Airway Surface Liquid Homeostasis.International journal of molecular sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 5 institutions in 2 countries.
Aleksandra BabichevaSection of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Ramon J AyonDepartments of Medicine and Physiology, The University of Arizona, Tucson, Arizona.
Tengteng ZhaoSection of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Jose F Ek VitorinDepartments of Medicine and Physiology, The University of Arizona, Tucson, Arizona.
Nicole M PohlDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois.
Aya YamamuraKinjo Gakuin University School of Pharmacy, Nagoya, Japan.
Hisao YamamuraNagoya City University Graduate School of Pharmaceutical Sciences, Nagoya, Japan.ORCID 0000-0001-8909-176X
Brooke A QuintonDepartments of Medicine and Physiology, The University of Arizona, Tucson, Arizona.
Manqing BaDepartments of Medicine and Physiology, The University of Arizona, Tucson, Arizona.
Linda WuDepartments of Medicine and Physiology, The University of Arizona, Tucson, Arizona.
Keeley S RavelletteDepartments of Medicine and Physiology, The University of Arizona, Tucson, Arizona.
Shamin RahimiSection of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Francesca BalistrieriSection of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Angela HarringtonSection of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
Rebecca R VanderpoolDepartments of Medicine and Physiology, The University of Arizona, Tucson, Arizona.ORCID 0000-0001-6038-0568
Patricia A ThistlethwaiteDepartment of Surgery, University of California, San Diego, La Jolla, California.
Ayako MakinoDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, California.
Jason X-J YuanSection of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, La Jolla, California.
University of Arizona · USUniversity of California San Diego · USKinjo Gakuin University · JPNagoya City University · JPUniversity of Illinois Chicago · US
Funding
Structure-Function Analysis of nmMLCK in EC Barrier ResponsesP01HL126609 · NHLBI · UNIVERSITY OF FLORIDA · PI Joe G. N. Garcia · 2016 to 2026
$24.4MIon Channels and Membrane Receptors in Pulmonary Arterial HypertensionR35HL135807 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YUAN, JASON X J · 2017 to 2023
$5.6MMolecular Mechanisms of Pulmonary HypertensionR01HL070852 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI THISTLETHWAITE, PATRICIA A · 2002 to 2011
$3.1MNOTCH3 Signaling in Pulmonary HypertensionR01HL119543 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI THISTLETHWAITE, PATRICIA A · 2014 to 2018
$2.2MRole of Gap Junction in Hypoxia-induced Pulmonary HypertensionR01HL146764 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MAKINO, AYAKO · 2019 to 2022
$1.6MNHLBI NIH HHS P01 HL126609NHLBI NIH HHS R01 HL070852NHLBI NIH HHS R01 HL119543NHLBI NIH HHS R01 HL146764NHLBI NIH HHS R35 HL135807
Abstract
Downregulated expression of K
Indexed as
AdolescentAdultCells, CulturedDown-RegulationFamilial Primary Pulmonary HypertensionFemaleHumansMaleMembrane PotentialsMicroRNAsMiddle AgedMuscle, Smooth, VascularMyocytes, Smooth MusclePotassium Channels, Voltage-GatedPulmonary ArteryRNA, MessengerMicroRNAsPotassium Channels, Voltage-GatedRNA, MessengerKCNA5KCNMB1microRNAposttranscriptional regulationpotassium channels
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.