ArticleJournal of the American Medical Informatics Association : JAMIA2019
Electronic medical record-based cohort selection and direct-to-patient, targeted recruitment: early efficacy and lessons learned.
Article in Journal of the American Medical Informatics Association : JAMIA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Recruitment of Black Adults into Cardiovascular Disease Trials.Journal of the American Heart Association · 2021Pooled it
- The Challenges of Enrollment and Retention: A Systematic Review of Psychosocial Behavioral Interventions for Patients With Cancer and Their Family Caregivers.Journal of pain and symptom management · 2021Pooled it
- A/B design testing of a clinical trial recruitment website: A pilot study to enhance the enrollment of older adults.Contemporary clinical trials · 2021Trial
- Social Media Influencer Marketing as a Clinical Trial Recruitment Modality: Tutorial Informed by One Study's Approach.Journal of medical Internet research · 2026Article
- A scoping review of studies on secure messaging through patient portals: persistent challenges and potential solutions.npj health systems · 2026Article
- Leveraging the PEDSnet clinical research network and electronic health record data to enhance efficiency of trial enrollment for a rare pediatric rheumatic disease.Pediatric rheumatology online journal · 2026Article
- Digital and community-engaged approaches to improve research participant recruitment - Advice from forty convened experts.Journal of clinical and translational science · 2026Article
- The Interplay of Neighborhood Deprivation, Race, and Multiple Sclerosis.Ethnicity & disease · 2026Article
- Improving Recruitment Into Research Studies via Electronically Collected Patient-Entered Data: Mixed Methods Study.Journal of medical Internet research · 2025Article
- Evaluating the Science of Diversity in Clinical Trials: Design and Goals of an American Heart Association Strategic Focused Research Network.Journal of the American Heart Association · 2025Article
- CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation.Journal of the American Heart Association · 2025Article
- Don't Count Them Out: Recruitment Strategies for Older Adults With Heart Failure.Journal of cardiac failure · 2025Article
- Patient Recruitment Strategies for Behavioral Clinical Trials in Adults with Inflammatory Bowel Diseases: An Analysis of the ADEPT (Addressing Disability Effectively with Psychosocial Telehealth) Randomized Controlled Trial.Crohn's & colitis 360 · 2025Article
- Domain-specific participant recruitment exceeds the application of "Targeted" advertisement from common online advertising platforms.Journal of clinical and translational science · 2025Article
- Addressing Statistical Power and Increasing Diversity in Hospice Research: Electronic Medical Record Participant Identification Compared to Nurse Referral Approaches to Recruitment.Journal of pain and symptom management · 2024Article
- Using patient portals for large-scale recruitment of individuals underrepresented in biomedical research: an evaluation of engagement patterns throughout the patient portal recruitment process at a single site within the All of Us Research Program.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Clinical Research Informatics: a Decade-in-Review.Yearbook of medical informatics · 2024Review
- Targeted electronic health record-based recruitment strategy to enhance COVID-19 vaccine response clinical research study enrollment.Contemporary clinical trials communications · 2024Article
- Clinical researchers' insights on key data for eligibility screening in clinical studies.Journal of clinical and translational science · 2024Article
- Implementation ofJournal of clinical and translational science · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
objectiveThe study sought to characterize institution-wide participation in secure messaging (SM) at a large academic health network, describe our experience with electronic medical record (EMR)-based cohort selection, and discuss the potential roles of SM for research recruitment. MATERIALS AND
methodsStudy teams defined eligibility criteria to create a computable phenotype, structured EMR data, to identify and recruit participants. Patients with SM accounts matching this phenotype received recruitment messages. We compared demographic characteristics across SM users and the overall health system. We also tabulated SM activation and use, characteristics of individual studies, and efficacy of the recruitment methods.
resultsOf the 1 308 820 patients in the health network, 40% had active SM accounts. SM users had a greater proportion of white and non-Hispanic patients than nonactive SM users id. Among the studies included (n = 13), 77% recruited participants with a specific disease or condition. All studies used demographic criteria for their phenotype, while 46% (n = 6) used demographic, disease, and healthcare utilization criteria. The average SM response rate was 2.9%, with higher rates among condition-specific (3.4%) vs general health (1.4%) studies. Those studies with a more inclusive comprehensive phenotype had a higher response rate. DISCUSSION: Target population and EMR queries (computable phenotypes) affect recruitment efficacy and should be considered when designing an EMR-based recruitment strategy.
conclusionsSM guided by EMR-based cohort selection is a promising approach to identify and enroll research participants. Efforts to increase the number of active SM users and response rate should be implemented to enhance the effectiveness of this recruitment strategy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.