ArticleSleep2020
Modeling the cardiometabolic benefits of sleep in older women: exploring the 24-hour day.
Article in Sleep, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Dose-response relationship of sleep apnea therapy and healthcare use in patients with comorbidities.Sleep · 2026Article
- Isotemporal substitution of sedentary time with physical activity for cardiovascular health in older adults: a systematic review.Frontiers in sports and active living · 2026Review
- The impact of exercise on women's health: A bibliometric and visualization analysis (2010-2024).Medicine · 2025Article
- Objective sleep monitoring at home in older adults: A scoping review.Journal of sleep research · 2025Article
- Methodological Choices on 24-h Movement Behavior Assessment by Accelerometry: A Scoping Review.Sports medicine - open · 2025Review
- Sleep and nighttime behavior disorders in older adults: associations with hypercholesterolemia and hypertriglyceridemia at baseline, and a predictive analysis of incident cases at 12 months follow-up.Lipids in health and disease · 2024Article
- Reallocating just 10 min to moderate-to-vigorous physical activity from other components of 24-hour movement behaviors improves cardiovascular health in adults.BMC public health · 2024Article
- High serum Cholesterol and Triglyceride levels in older adults: associations with sleep and nighttime behavior disorders at baseline and a prediction analysis of incidental cases at 12 months follow-up.medRxiv : the preprint server for health sciences · 2024Article
- Article
- Rest-activity rhythms and cognitive impairment and dementia in older women: Results from the Women's Health Initiative.Journal of the American Geriatrics Society · 2022Article
- Article
- Isotemporal Substitution of Time Between Sleep and Physical Activity: Associations With Cardiovascular Risk Factors in Early Rheumatoid Arthritis.ACR open rheumatology · 2021Article
- Beyond the absence of sleep disorder: spotlighting the cardiovascular benefits of sleep health.Sleep science (Sao Paulo, Brazil)Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
STUDY
objectivesActivities throughout the day, including sleep, sedentary behavior (SB), light-intensity physical activity (LIPA), and moderate to vigorous physical activity (MVPA) are independently associated with cardiometabolic health. Few studies have examined interrelationships between sleep and 24-hour activity and associations with cardiometabolic risk. The objective of this study is to understand how replacing time in SB, LIPA, or MVPA with sleep impacts cardiometabolic risk.
methodsWomen's Health Initiative OPACH Study participants (N = 3329; mean age = 78.5 ± 6) wore ActiGraph GT3X+ accelerometers 24 hours/7 days. Adjusted linear regression estimated the relationship between sleep duration and cardiometabolic markers. Separately for shorter (<8 hours) and longer (≥8 hours) sleepers, isotemporal substitution models estimated the cross-sectional associations with cardiometabolic markers with reallocating time in daytime activities to or from sleep.
resultsLonger sleep duration was associated with higher insulin, HOMA-IR, glucose, total cholesterol, and triglycerides (all p < 0.05). The associations between sleep duration and C-reactive protein, waist circumference, and body mass index (BMI) were U-shaped (both p < 0.05). For shorter sleepers, reallocating 33 minutes of MVPA to sleep was associated with higher values of insulin, HOMA-IR, glucose, triglycerides, waist circumference, and BMI (0.7%-11.5%). Replacing 91 minutes of SB time with sleep was associated with lower waist circumference and BMI (-1.3%, -1.8%). For long sleepers, shifting 91 minutes of sleep to SB was associated with higher waist circumference and BMI (1.3%, 1.4%).
conclusionsThis is one of the first isotemporal analyses to include objectively measured sleep duration. Results illuminate possible cardiometabolic risks and benefits of reallocating time to or from sleep.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.