Evidence map›Paper›PMID 31552826›Full record

ArticleeLife2019

A tissue-like platform for studying engineered quiescent human T-cells' interactions with dendritic cells.

Enas Abu-Shah, Philippos Demetriou, Štefan Bálint, Viveka Mayya, Mikhail A Kutuzov, Omer Dushek, Michael L Dustin

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Human CD8Journal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Enas Abu-ShahKennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-5033-8171
Philippos Demetriou *Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.
Štefan Bálint *Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-4470-5881
Viveka MayyaKennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-5668-9124
Mikhail A KutuzovSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Omer DushekSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-5847-5226
Michael L DustinKennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-4983-6389

Funding

European Research Council ERC-2014-AdG_670930Wellcome Trust 100262Z/12/ZWellcome Trust 207537/Z/17/Z
6 · The paper itself

Abstract

Research in the field of human immunology is restricted by the lack of a system that reconstitutes the

Indexed as

Antigen PresentationAntigen-Presenting CellsAntigensCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell CommunicationCells, CulturedCytokinesDendritic CellsHumansImmune SystemLymphocyte ActivationAntigensCytokines3D model systemantigen presenting cellshumanhuman biologyimmunologyimmunotherapyinflammationmedicineT-cellsTCR engineering

Identifiers

PMID31552826
PMCPMC6910819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.