Evidence map›Paper›PMID 31552697›Full record

ArticleJournal of cardiovascular electrophysiology2019

STAR mapping method to identify driving sites in persistent atrial fibrillation: Application through sequential mapping.

Shohreh Honarbakhsh, Richard J Schilling, Malcolm Finlay, Emily Keating, Waqas Ullah, Ross J Hunter

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04442113 (Multicenter Randomized Controlled Trial Assessing Targeted Ablation in Persistent Atrial Fibrillation Using the Stochastic Trajectory Analysis of Ranked Signals), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04442113 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Multicenter Randomized Controlled Trial Assessing Targeted Ablation in Persistent Atrial Fibrillation Using the Stochastic Trajectory Analysis of Ranked Signals (STAR Mapping™) Method.

TypeinterventionalSponsorRhythm AI LtdRan2021 to 2022Enrolled0ConditionsAtrial FibrillationArmsPulmonary vein isolation plus ablation guided by novel STAR mapping™, Pulmonary vein isolation
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Electrographic flow mapping for atrial fibrillation: theoretical basis and preliminary observations.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Is there rule to the chaos: Defining stable patterns in atrial fibrillation.Journal of cardiovascular electrophysiology · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shohreh HonarbakhshElectrophysiology department, The Barts Heart Centre, London, United Kingdom.ORCID 0000-0003-0081-5739
Richard J SchillingElectrophysiology department, The Barts Heart Centre, London, United Kingdom.
Malcolm FinlayElectrophysiology department, The Barts Heart Centre, London, United Kingdom.
Emily KeatingElectrophysiology department, The Barts Heart Centre, London, United Kingdom.
Waqas UllahElectrophysiology department, The Barts Heart Centre, London, United Kingdom.
Ross J HunterElectrophysiology department, The Barts Heart Centre, London, United Kingdom.

Funding

British Heart Foundation PG/16/10/32016
6 · The paper itself

Abstract

introductionThe optimal way to map localized drivers in persistent atrial fibrillation (AF) remains unclear. The objective of the study was to apply a novel vector mapping approach called Stochastic Trajectory Analysis of Ranked signals (STAR) in AF. METHODS AND

resultsPatients having persistent AF ablation were included. Early sites of activation (ESA) identified on global STAR maps created with basket catheters were used to guide AF ablation post-pulmonary vein isolation (PVI). All patients also had sequential STAR maps created with ≥10 PentaRay recordings of 30 seconds. These were validated offline in their ability to identify the ESA targeted with a study-defined ablation response (AF termination or cycle length [CL] slowing of ≥30 ms). Thirty-two patients were included in whom 92 ESA were identified on the global STAR maps, with 73 of 83 targeted sites demonstrating an ablation response (24 AF termination and 49 CL slowing). Sixty-one out of 73 (83.6%) ESA were also identified on the sequential STAR maps. These showed greater consistency (P < .001), were seen pre- and post-PVI (P < .001) and were more likely to be associated with AF termination on ablation (P = .007). The sensitivity and specificity of sequential mapping for the detection of ESA with an ablation response was 84.9% (95% confidence interval [CI] = 74.6-92.2) and 90.0% (95% CI = 55.5-99.8), respectively. During a follow-up of 19.4 ± 3.7 months, 28 (80%) patients were free from AF/atrial tachycardia.

conclusionsSTAR mapping consistently identified ESA in all patients and the ablation response was compatible with ESA being driver sites. Mechanistically important ESA were successfully identified using sequential recordings.

Indexed as

Action PotentialsElectrophysiologic Techniques, CardiacHeart RateSignal Processing, Computer-AssistedAgedAtrial FibrillationCatheter AblationFemaleHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesPulmonary VeinsRecurrenceReproducibility of Resultsatrial fibrillationatrial tachycardiacatheter ablationdriversmapping

Identifiers

PMID31552697
PMCPMC6916564

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.