Evidence map›Paper›PMID 31552436›Full record

ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2019

[Fluorescence-guided detection of lymph node metastases of gastrointestinal tumors].

Andrea Picchetto, Barbara Seeliger, Stefania La Rocca, Manuel Barberio, Giancarlo D'Ambrosio, Jacques Marescaux, Michele Diana

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. History and evidence for state of the art of lymphadenectomy in esophageal cancer surgery.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Andrea PicchettoGeneral and Colorectal Surgery Division, Department of Cardiothoracic, Vascular Surgery and Organ Transplantation, Policlinico Umberto I University Hospital, Sapienza University of Rome, Viale del Policlinico 155, Rom, Italien. andrea.picchetto@uniroma1.it.
Barbara SeeligerInstitute of Image-Guided Surgery, IHU-Strasbourg, Straßburg, Frankreich.
Stefania La RoccaGeneral and Colorectal Surgery Division, Department of Cardiothoracic, Vascular Surgery and Organ Transplantation, Policlinico Umberto I University Hospital, Sapienza University of Rome, Viale del Policlinico 155, Rom, Italien.
Manuel BarberioInstitute of Image-Guided Surgery, IHU-Strasbourg, Straßburg, Frankreich.
Giancarlo D'AmbrosioGeneral and Colorectal Surgery Division, Department of Cardiothoracic, Vascular Surgery and Organ Transplantation, Policlinico Umberto I University Hospital, Sapienza University of Rome, Viale del Policlinico 155, Rom, Italien.
Jacques MarescauxInstitute of Image-Guided Surgery, IHU-Strasbourg, Straßburg, Frankreich.
Michele DianaInstitute of Image-Guided Surgery, IHU-Strasbourg, Straßburg, Frankreich.
Institut de Chirurgie Guidée par l'Image · FRSapienza University of Rome · ITInstitut de Recherche contre les Cancers de l’Appareil Digestif · FRKliniken Essen-Mitte · DEPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A correct lymph node (LN) staging is essential in oncological surgery. Indocyanine green (ICG) near-infrared fluorescence (NIRF) guided sentinel lymph node (SLN) navigation is a relatively novel technique. The aim of this review is to analyze the impact of ICG-NIRF on identification of LN metastases of gastrointestinal tumors. The Scopus and PubMed/MEDLINE literature databases were searched and 20 studies were included. The ICG-NIRF navigation of LN has been shown to enable and improve LN detection in gastrointestinal tumors; however, the mean detection, sensitivity, accuracy and false negative rates show substantial variation. This could be due to both the heterogeneous techniques applied and to the low retention of ICG by lymph nodes. Fluorescence imaging to identify LN drainage is a promising tool to improve oncological outcomes. Nonetheless, the technique requires further development in terms of hardware, software and fluorophores, which are currently being investigated.

Indexed as

Gastrointestinal NeoplasmsSentinel Lymph Node BiopsyFluorescent DyesHumansIndocyanine GreenLymphatic MetastasisLymph NodesOptical ImagingFluorescent DyesIndocyanine GreenColorectal cancerEsophageal cancerGastric cancerNear-infrared fluorescence imagingSentinel lymph node mapping

Identifiers

PMID31552436
OpenAlexW2977009282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.