Evidence map›Paper›PMID 31552374›Full record

ArticleACS omega2019

Optimization and Structural Stability of Gold Nanoparticle-Antibody Bioconjugates.

Robert T Busch, Farzia Karim, John Weis, Yvonne Sun, Chenglong Zhao, Erick S Vasquez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
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  10. Review
  11. Antibody-Nanoparticle Conjugates in Therapy: Combining the Best of Two Worlds.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  12. Click Chemistry-Based Bioconjugation of Iron Oxide Nanoparticles.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert T BuschDepartment of Chemical and Materials Engineering, Department of Electro-Optics and Photonics, Department of Biology, Integrative Science and Engineering Center, and Department of Physics, University of Dayton, 300 College Park, Dayton, Ohio 45469, United States.
Farzia KarimDepartment of Chemical and Materials Engineering, Department of Electro-Optics and Photonics, Department of Biology, Integrative Science and Engineering Center, and Department of Physics, University of Dayton, 300 College Park, Dayton, Ohio 45469, United States.
John WeisDepartment of Chemical and Materials Engineering, Department of Electro-Optics and Photonics, Department of Biology, Integrative Science and Engineering Center, and Department of Physics, University of Dayton, 300 College Park, Dayton, Ohio 45469, United States.
Yvonne SunDepartment of Chemical and Materials Engineering, Department of Electro-Optics and Photonics, Department of Biology, Integrative Science and Engineering Center, and Department of Physics, University of Dayton, 300 College Park, Dayton, Ohio 45469, United States.
Chenglong ZhaoDepartment of Chemical and Materials Engineering, Department of Electro-Optics and Photonics, Department of Biology, Integrative Science and Engineering Center, and Department of Physics, University of Dayton, 300 College Park, Dayton, Ohio 45469, United States.
Erick S VasquezDepartment of Chemical and Materials Engineering, Department of Electro-Optics and Photonics, Department of Biology, Integrative Science and Engineering Center, and Department of Physics, University of Dayton, 300 College Park, Dayton, Ohio 45469, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) bound with biomolecules have emerged as suitable biosensors exploiting unique surface chemistries and optical properties. Many efforts have focused on antibody bioconjugation to AuNPs resulting in a sensitive bioconjugate to detect specific types of bacteria. Unfortunately, bacteria thrive under various harsh environments, and an understanding of bioconjugate stability is needed. Here, we show a method for optimizing

Identifiers

PMID31552374
PMCPMC6751724

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.