Evidence map›Paper›PMID 31552259›Full record

ReviewFrontiers in nutrition2019

Nutrition Interventions in Rheumatoid Arthritis: The Potential Use of Plant-Based Diets. A Review.

Jihad Alwarith, Hana Kahleova, Emilie Rembert, Willy Yonas, Sara Dort, Manuel Calcagno, Nora Burgess, Lee Crosby, Neal D Barnard

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 3 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jihad AlwarithPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Hana KahleovaPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Emilie RembertPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Willy YonasPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Sara DortPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Manuel CalcagnoPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Nora BurgessPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Lee CrosbyPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Neal D BarnardPhysicians Committee for Responsible Medicine, Washington, DC, United States.
Physicians Committee for Responsible Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA), a chronic inflammatory autoimmune disease, affects roughly 1% of the world's population. RA pathogenesis remains unclear, but genetic factors account for 50-60% of the risk while the remainder might be linked to modifiable factors, such as infectious diseases, tobacco smoking, gut bacteria, and nutrition. Dietary triggers may play an inciting role in the autoimmune process, and a compromised intestinal barrier may allow food components or microorganisms to enter the blood stream, triggering inflammation. In addition, excessive body weight may affect pharmacotherapy response and the likelihood of disease remission, as well as the risk of disease mortality. Evidence suggests that changes in diet might play an important role in RA management and remission. Several studies have shown improvements in RA symptoms with diets excluding animal products. Studies have also shown that dietary fiber found in these plant-based foods can improve gut bacteria composition and increase bacterial diversity in RA patients, thus reducing their inflammation and joint pain. Although some of the trigger foods in RA patients are individualized, a vegan diet helps improve symptoms by eliminating many of these foods. This review examines the potential role of a plant-based diet in mediating RA symptoms. Further research is needed to test the effectiveness of plant-based diets on joint pain, inflammation, and quality of life in patients with RA.

Indexed as

autoimmunedietinflammationplant-basedrheumatoid arthritisveganvegetarian

Identifiers

PMID31552259
PMCPMC6746966
OpenAlexW2968539995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.