Evidence map›Paper›PMID 31552201›Full record

ArticleFrontiers in cellular and infection microbiology2019

Activation of Mast Cells Promote

Bo Huang, Shiguang Huang, Xiaoyan Chen, Xiao Bo Liu, Qiang Wu, Yongfei Wang, Xiaobo Li, Kunning Li, Hongzhi Gao, Shan Cen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Here, There, and Everywhere: Myeloid-Derived Suppressor Cells in Immunology.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  6. Biotechnologia · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Mast Cells in the Skin: Defenders of Integrity or Offenders in Inflammation?International journal of molecular sciences · 2021
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Bo HuangGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Shiguang HuangSchool of Stomatology, Jinan University, Guangzhou, China.
Xiaoyan ChenGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Xiao Bo LiuDepartment of Pathogen Biology and Immunology, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Qiang WuDepartment of Pathogen Biology and Immunology, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Yongfei WangCollege of Life Science and Technology, Jinan University, Guangzhou, China.
Xiaobo LiDepartment of Pathogen Biology and Immunology, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Kunning LiLady Davis institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Hongzhi GaoDepartment of Neurosurgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Shan CenDepartment of Immunology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China.
Rongtuan LinDivision of Experimental Medicine, Department of Medicine, McGill University, Montreal, QC, Canada.
Zhenlong LiuDivision of Experimental Medicine, Department of Medicine, McGill University, Montreal, QC, Canada.
Xiaobao JinGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Guangdong Pharmaceutical University · CNMcGill University · CAJinan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNFujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria, a mosquito-borne infectious disease, is a severe health problem worldwide. As reported, some anti-malarial drugs with anti-parasitic properties also block mast cells (MCs) activities. It is hypothesized that MCs activity may be correlated with the pathogenesis of malaria. Thus, the role of MCs on malarial pathogenesis and the involved physiological action and pathways need to be further investigated. This study aimed to investigate the effect of MCs activation on malaria disease severity using KunMing mice with

Indexed as

AnimalsCromolyn SodiumCytokinesDisease Models, AnimalImmunologic FactorsLymph NodesMalariaMast CellsMiceParasitemiaPlasmodium bergheip-Methoxy-N-methylphenethylamineSkinSurvival AnalysisCromolyn SodiumCytokinesImmunologic Factorsp-Methoxy-N-methylphenethylaminedegranulationimmune responsesmast cellspathogenesisPlasmodium bergheivascular permeability

Identifiers

PMID31552201
PMCPMC6747038
OpenAlexW2970952647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.