Evidence map›Paper›PMID 31552196›Full record

ReviewFrontiers in cellular and infection microbiology2019

Maintaining Integrity Under Stress: Envelope Stress Response Regulation of Pathogenesis in Gram-Negative Bacteria.

Claire L Hews, Timothy Cho, Gary Rowley, Tracy L Raivio

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed.

  1. The divergentMicrobiology (Reading, England) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. ThemBio · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. UnveilingFoods (Basel, Switzerland) · 2025
    Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Claire L HewsSchool of Biological Sciences, University of East Anglia, Norwich, United Kingdom.
Timothy ChoDepartment of Biological Sciences, University of Alberta, Edmonton, AB, Canada.
Gary RowleySchool of Biological Sciences, University of East Anglia, Norwich, United Kingdom.
Tracy L RaivioDepartment of Biological Sciences, University of Alberta, Edmonton, AB, Canada.

Funding

Biotechnology and Biological Sciences Research Council BB/M011216/1CIHR MOP 342982
6 · The paper itself

Abstract

The Gram-negative bacterial envelope is an essential interface between the intracellular and harsh extracellular environment. Envelope stress responses (ESRs) are crucial to the maintenance of this barrier and function to detect and respond to perturbations in the envelope, caused by environmental stresses. Pathogenic bacteria are exposed to an array of challenging and stressful conditions during their lifecycle and, in particular, during infection of a host. As such, maintenance of envelope homeostasis is essential to their ability to successfully cause infection. This review will discuss our current understanding of the σ

Indexed as

Stress, PhysiologicalAdaptation, PhysiologicalCell MembraneCell WallGene Expression Regulation, BacterialGene Regulatory NetworksGram-Negative BacteriaCpx responseenvelope stressGram-negative bacteriapathogenesissigmaE response

Identifiers

PMID31552196
PMCPMC6737893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.