Evidence map›Paper›PMID 31552142›Full record

ArticleCell death discovery2019

Extracellular annexin-A1 promotes myeloid/granulocytic differentiation of hematopoietic stem/progenitor cells via the Ca

Christiano M V Barbosa, Ricardo Ambrósio Fock, Araceli Aparecida Hastreiter, Cris Reutelingsperger, Mauro Perretti, Edgar J Paredes-Gamero, Sandra H P Farsky

Open access · goldAbstract read
In one paragraph

Article in Cell death discovery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. M2 Macrophage-Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  6. Review
  7. Article
  8. Ablation ofPNAS nexus · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Phospholipase ACells · 2021
    Review
  20. Annexin Animal Models-From Fundamental Principles to Translational Research.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Christiano M V Barbosa1Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Sao Paulo, Brazil.
Ricardo Ambrósio Fock1Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Sao Paulo, Brazil.
Araceli Aparecida Hastreiter1Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Sao Paulo, Brazil.
Cris Reutelingsperger2CARIM School for Cardiovascular Diseases, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-2334-9403
Mauro Perretti4The William Harvey Research Institute, Bart's and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0003-2068-3331
Edgar J Paredes-Gamero5Department of Biochemistry, Federal University of São Paulo, São Paulo, Brazil.
Sandra H P Farsky1Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, Sao Paulo, Brazil.ORCID 0000-0002-3943-977X
Universidade de São Paulo · BRMaastricht University · NLQueen Mary University of London · GBUniversidade Federal de Mato Grosso do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Annexin A1 (AnxA1) modulates neutrophil life span and bone marrow/blood cell trafficking thorough activation of formyl-peptide receptors (FPRs). Here, we investigated the effect of exogenous AnxA1 on haematopoiesis in the mouse. Treatment of C57BL/6 mice with recombinant AnxA1 (rAnxA1) reduced the granulocyte-macrophage progenitor (GMP) population in the bone marrow, enhanced the number of mature granulocytes Gr-1

Indexed as

Calcium signallingRecombinant protein therapy

Identifiers

PMID31552142
PMCPMC6755131
OpenAlexW2974047570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.