Evidence map›Paper›PMID 31552057›Full record

ArticleFrontiers in immunology2019

Cardiotrophin-Like Cytokine Factor 1 Exhibits a Myeloid-Biased Hematopoietic-Stimulating Function.

Sarah Pasquin, Aurélie Tormo, Jessica Moreau, Véronique Laplante, Mukut Sharma, Jean-François Gauchat, Moutih Rafei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. CRLF1 and CLCF1 in Development, Health and Disease.International journal of molecular sciences · 2022
    Review
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sarah PasquinDépartement de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada.
Aurélie TormoDépartement de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada.
Jessica MoreauDépartement de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada.
Véronique LaplanteDépartement de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada.
Mukut SharmaRenal Division, KCVA Medical Center, Kansas City, MO, United States.
Jean-François GauchatDépartement de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada.
Moutih RafeiDépartement de Pharmacologie et Physiologie, Université de Montréal, Montreal, QC, Canada.
Université de Montréal · CAKansas City VA Medical Center · US

Funding

CIHR MOP 57832CIHR PJT 159654
6 · The paper itself

Abstract

Cardiotrophin-like cytokine factor 1 (CLCF1) is secreted as a complex with the cytokine receptor-like factor 1 (CRLF1). Syndromes caused by mutations in the genes encoding CLCF1 or CRLF1 suggest an important role for CLCF1 in the development and regulation of the immune system. In mice, CLCF1 induces B-cell expansion, enhances humoral responses and triggers autoimmunity. Interestingly, inactivation of

Indexed as

HematopoiesisAnimalsFemaleMice, Inbred C57BLMyeloid Progenitor CellsReceptors, CytokineRecombinant Proteinscytokine-like factor-1Receptors, CytokineRecombinant Proteinsbone marrow transplantationcardiotrophin-like cytokine factor 1interleukin-6LSK cellsmyelopoiesis

Identifiers

PMID31552057
PMCPMC6746841
OpenAlexW2969409355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.