Evidence map›Paper›PMID 31552045›Full record

ReviewFrontiers in immunology2019

Toward T Cell-Mediated Control or Elimination of HIV Reservoirs: Lessons From Cancer Immunology.

Geetha Mylvaganam, Adrienne G Yanez, Marcela Maus, Bruce D Walker

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. CD8Heliyon · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. HIV cure strategies: which ones are appropriate for Africa?Cellular and molecular life sciences : CMLS · 2022
    Review
  11. Role of CXCR5Frontiers in microbiology · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Broadly active zinc finger protein-guided transcriptional activation of HIV-1.Molecular therapy. Methods & clinical development · 2021
    Article
  16. Article
  17. Review
  18. Targeting Epigenetics to Cure HIV-1: Lessons From (and for) Cancer Treatment.Frontiers in cellular and infection microbiology · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Geetha MylvaganamRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Adrienne G YanezRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Marcela MausRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Bruce D WalkerRagon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Ragon Institute of MGH, MIT and Harvard · USGlobal Cancer Institute · US

Funding

Support Component D/Vaccine Discovery, Concept to ClinicUM1AI100663 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BAROUCH, DAN H. · 2012 to 2018
$131.5M
NIAID NIH HHS UM1 AI100663
6 · The paper itself

Abstract

As the AIDS epidemic unfolded, the appearance of opportunistic infections in at-risk persons provided clues to the underlying problem: a dramatic defect in cell-mediated immunity associated with infection and depletion of CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHIV-1HIV InfectionsHumansImmune ToleranceImmunity, CellularImmunotherapy, AdoptiveLymphoid TissueNeoplasmsProgrammed Cell Death 1 ReceptorRemission, SpontaneousTumor MicroenvironmentVirus LatencyProgrammed Cell Death 1 ReceptorcancerCTL (cytotoxic T lymphocyte)HIVimmunothearpyremission

Identifiers

PMID31552045
PMCPMC6746828
OpenAlexW2969930107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.