Evidence map›Paper›PMID 31552030›Full record

ArticleFrontiers in immunology2019

CXCR5

Richard Danger, Mélanie Chesneau, Florent Delbos, Sabine Le Bot, Clarisse Kerleau, Alexis Chenouard, Simon Ville, Nicolas Degauque, Sophie Conchon, Anne Cesbron and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Targeting THaematologica · 2024
    Article
  4. Activation and Regulation of Indirect Alloresponses in Transplanted Patients With Donor Specific Antibodies and Chronic Rejection.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. The Ratio of CD226 and TIGIT Expression in Tfh and PD-1Journal of immunology research · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. CD4Frontiers in immunology · 2022
    Review
  15. Review
  16. Article
  17. Therapies for Chronic Allograft Rejection.Frontiers in pharmacology · 2021
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Richard DangerCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Mélanie ChesneauCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Florent DelbosLaboratoire Histocompatibilité et Immunogénétique - Etablissement Français du sang, Nantes, France.
Sabine Le BotCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Clarisse KerleauCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Alexis ChenouardCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Simon VilleInstitut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes, Nantes, France.
Nicolas DegauqueCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Sophie ConchonCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Anne CesbronLaboratoire Histocompatibilité et Immunogénétique - Etablissement Français du sang, Nantes, France.
Magali GiralCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Sophie BrouardCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Université de Nantes, Nantes, France.
Inserm · FRInstitut de Transplantation Urologie en Nephrologie · FRÉtablissement Français du Sang · FRNantes Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Donor-specific anti-HLA antibodies (DSAs) are a major risk factor associated with renal allograft outcomes. As a trigger of B cell antibody production, T follicular helper cells (Tfhs) promote DSA appearance. Herein, we evaluated whether circulating Tfhs (cTfhs) are associated with the genesis of antibody-mediated rejection. We measured cTfh levels on the day of transplantation and 1 year after transplantation in blood from a prospective cohort of 237 renal transplantation patients without DSA during the first year post-transplantation. Total cTfhs were characterized as CD4

Indexed as

AdultFemaleHLA AntigensHumansInducible T-Cell Co-Stimulator ProteinIsoantibodiesKidney TransplantationMaleMiddle AgedPhenotypeProgrammed Cell Death 1 ReceptorReceptors, CXCR5Tissue DonorsT-Lymphocytes, Helper-InducerHLA AntigensICOS protein, humanInducible T-Cell Co-Stimulator ProteinIsoantibodiesPDCD1 protein, humanProgrammed Cell Death 1 ReceptorReceptors, CXCR5circulating T follicular helper lymphocytesdonor-specific antibodiesDSArenal transplantationTfh

Identifiers

PMID31552030
PMCPMC6746839
OpenAlexW2969062831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.