ArticleFrontiers in immunology2019
Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer.
Open access · goldAbstract read
In one paragraph
Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers.
0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
112 citing papers in PubMed, 196 citations in OpenAlex.
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Axatilimab in Healthy Japanese Male Participants: Results from a Phase 1, Randomized, Double-Blind, Dose-Escalation Study.Clinical drug investigation · 2025Trial
- The roles of microglia and astrocytes in inflammasomes and neurological disorders.Neural regeneration research · 2026Article
- Targeting Post-Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual-Action Approach for Antioxidant and Immune Modulation.Advanced healthcare materials · 2026Article
- Transcriptome of the human C2 dorsal root ganglia in C1-2 arthrodesis surgery: insight for neck pain.Brain : a journal of neurology · 2026Article
- Computational design of synthetic receptors with programmable signalling activity for enhanced cancer T cell therapy.Nature biomedical engineering · 2026Article
- Spatial Transcriptomics Reveals Injured Cells, Signature Genes, and Communication Patterns in the Cyst Microenvironment of Polycystic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2026Article
- Macrophages regulate meiotic initiation and germ cell clearance in the developing ovary.bioRxiv : the preprint server for biology · 2026Article
- Amplified inflammatory and immune responses in viral-associated pulmonary aspergillosis.Frontiers in cellular and infection microbiology · 2026Article
- Roles of IL-34 in neurological diseases: neuroprotection, inflammatory regulation, and myeloid plasticity.Frontiers in immunology · 2026Review
- Spatiotemporal dynamics of neuronal subtypes and their interactions with glia following intracortical electrode implantation.Biology direct · 2025Article
- Identification and validation of microglia-associated genes in ischemic stroke using single-cell and bulk RNA-seq.Molecular brain · 2025Article
- CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion.Cancer biology & therapy · 2025Article
- Targeting CSF-1 signaling between tumor cells and macrophages at TMEM doorways inhibits breast cancer dissemination.Oncogene · 2025Article
- Treatment Resistant Persister Cells Exploit Macrophage Lipid Metabolism to Sustain Glioblastoma Growth.bioRxiv : the preprint server for biology · 2025Article
- Maraviroc Prevents Optic Nerve Injury-Induced Retinal Ganglion Cell Apoptosis by Modulating the CCL5/CCR5/CTSS Axis.Investigative ophthalmology & visual science · 2025Article
- Single nucleotide polymorphism-based analysis of linkage disequilibrium and runs of homozygosity patterns of indigenous sheep in the southern Taklamakan desert.BMC genomics · 2025Article
- Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis.eLife · 2025Article
- Intestinal epithelium-derived IL-34 reprograms macrophages to mitigate gastrointestinal tract graft-versus-host disease.Science translational medicine · 2025Article
- Transcriptomic profiling of granuloma in patients with cardiac sarcoidosis.Theranostics · 2025Article
- Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma.Cancer immunology, immunotherapy : CII · 2024Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
48 authors.
WeiYu LinGenentech, South San Francisco, CA, United States.
Daqi XuGenentech, South San Francisco, CA, United States.
Cary D AustinGenentech, South San Francisco, CA, United States.
Patrick CaplaziGenentech, South San Francisco, CA, United States.
Kate SengerGenentech, South San Francisco, CA, United States.
Yonglian SunGenentech, South San Francisco, CA, United States.
Surinder JeetGenentech, South San Francisco, CA, United States.
Judy YoungGenentech, South San Francisco, CA, United States.
Donnie DelarosaGenentech, South San Francisco, CA, United States.
Eric SutoGenentech, South San Francisco, CA, United States.
Zhiyu HuangGenentech, South San Francisco, CA, United States.
Juan ZhangGenentech, South San Francisco, CA, United States.
Donghong YanGenentech, South San Francisco, CA, United States.
Cesar CorzoGenentech, South San Francisco, CA, United States.
Kai BarckGenentech, South San Francisco, CA, United States.
Sharmila RajanGenentech, South San Francisco, CA, United States.
Carrie LooneyGenentech, South San Francisco, CA, United States.
Vineela GandhamGenentech, South San Francisco, CA, United States.
Justin LeschGenentech, South San Francisco, CA, United States.
Wei-Ching LiangGenentech, South San Francisco, CA, United States.
Elaine MaiGenentech, South San Francisco, CA, United States.
Hai NguGenentech, South San Francisco, CA, United States.
Navneet RattiGenentech, South San Francisco, CA, United States.
Yongmei ChenGenentech, South San Francisco, CA, United States.
Dinah MisnerGenentech, South San Francisco, CA, United States.
Tori LinGenentech, South San Francisco, CA, United States.
Dimitry DanilenkoGenentech, South San Francisco, CA, United States.
Paula KatavolosGenentech, South San Francisco, CA, United States.
Estelle DoudemontGenentech, South San Francisco, CA, United States.
Hirdesh UppalGenentech, South San Francisco, CA, United States.
Jeffrey EasthamGenentech, South San Francisco, CA, United States.
Judy MakGenentech, South San Francisco, CA, United States.
Patricia E de AlmeidaGenentech, South San Francisco, CA, United States.
Katherine BaoGenentech, South San Francisco, CA, United States.
Azadeh HadadianpourGenentech, South San Francisco, CA, United States.
Mary KeirGenentech, South San Francisco, CA, United States.
Richard A D CaranoGenentech, South San Francisco, CA, United States.
Lauri DiehlGenentech, South San Francisco, CA, United States.
Min XuGenentech, South San Francisco, CA, United States.
Yan WuGenentech, South San Francisco, CA, United States.
Robby M WeimerGenentech, South San Francisco, CA, United States.
Jason DeVossGenentech, South San Francisco, CA, United States.
Wyne P LeeGenentech, South San Francisco, CA, United States.
Mercedesz BalazsGenentech, South San Francisco, CA, United States.
Kevin WalshGenentech, South San Francisco, CA, United States.
Kathila R AlatsisGenentech, South San Francisco, CA, United States.
Flavius MartinGenentech, South San Francisco, CA, United States.
Ali A ZarrinGenentech, South San Francisco, CA, United States.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal
Indexed as
AnimalsCell DifferentiationDisease Models, AnimalHomeostasisHumansInflammationInterleukinsMacrophage Colony-Stimulating FactorMacrophagesMaleMice, Inbred BALB CMice, Inbred C57BLMice, Inbred DBAMice, Inbred NZBMice, KnockoutMyeloid Cellsinterleukin-34, mouseInterleukinsMacrophage Colony-Stimulating FactorcancerCSF1 and Il34 inhibitionCSF1RinflammationLangerhans cellsmacrophagemicrogliamonocyte
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.