Evidence map›Paper›PMID 31551983›Full record

ArticleFrontiers in microbiology2019

Quorum Quenching Lactonase Strengthens Bacteriophage and Antibiotic Arsenal Against

Sonia Mion, Benjamin Rémy, Laure Plener, Fabienne Brégeon, Eric Chabrière, David Daudé

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Phages and quorum sensing: findings to consider in phage therapy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  5. Review
  6. Review
  7. Antibiotic-ResistantMicroorganisms · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Thermostable Lactonases InhibitInternational journal of molecular sciences · 2023
    Article
  13. Heliyon · 2023
    Article
  14. Mechanisms regulating the CRISPR-Cas systems.Frontiers in microbiology · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sonia MionAix-Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France.
Benjamin RémyAix-Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France.
Laure PlenerGene&GreenTK, Marseille, France.
Fabienne BrégeonAix-Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France.
Eric ChabrièreAix-Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France.
David DaudéGene&GreenTK, Marseille, France.
Aix-Marseille Université · FRGene and GreenTK (France) · FRMéditerranée Infection Foundation · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many bacteria use quorum sensing (QS), a bacterial communication system based on the diffusion and perception of small signaling molecules, to synchronize their behavior in a cell-density dependent manner. QS regulates the expression of many genes associated with virulence factor production and biofilm formation. This latter is known to be involved in antibiotic and phage resistance mechanisms. Therefore, disrupting QS, a strategy known as quorum quenching (QQ), appears to be an interesting way to reduce bacterial virulence and increase antibiotic and phage treatment efficiency. In this study, the ability of the QQ enzyme

Indexed as

AHLantibioticsbacteriophageslactonasemultidrug resistant bacteriaPseudomonas aeruginosaquorum quenchingquorum sensing

Identifiers

PMID31551983
PMCPMC6734170
OpenAlexW2969759331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.