Evidence map›Paper›PMID 31551961›Full record

ArticleFrontiers in microbiology2019

Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic

Vivek Verma, Surbhi Gupta, Parveen Kumar, Sonal Yadav, Rakesh Singh Dhanda, Rajni Gaind, Renu Arora, Niels Frimodt-Møller, Manisha Yadav

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Vivek VermaDr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, India.
Surbhi GuptaDr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, India.
Parveen KumarDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, United States.
Sonal YadavDr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, India.
Rakesh Singh DhandaStem Cell Laboratory, Longboat Explorers AB, SMiLE Incubator, Lund, Sweden.
Rajni GaindDepartment of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Renu AroraDepartment of Obstetrics and Gynecology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Niels Frimodt-MøllerDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark.
Manisha YadavDr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, India.
University of Delhi · INVardhman Mahavir Medical College & Safdarjung Hospital · INAmbedkar University Delhi · INRigshospitalet · DKUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory response during urinary tract infection (UTI) is mediated by innate immune defense. Nod like receptors (NLRs) have been proposed to work simultaneously beside TLR pathways to mediate pro-inflammatory response and maintain tissue homeostasis. Some

methodsA total of 186 females experiencing the first episode of UTI were recruited for the study and forty were found to be positive for UPEC (≥10

resultsMost of the inflammatory regulators studied (i.e.,

conclusionInvolvement of

Indexed as

inflammasomesNLRC4NLRP3nod like receptors (NLR)urinary tract infection (UTI)uropathogenic Escherichia coli (UPEC)

Identifiers

PMID31551961
PMCPMC6734172
OpenAlexW2969435609

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.