ReviewFrontiers in neurology2019
Review in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Pooled it
- Phenotype Refinement Influences GWAS-Implicated Variant Effect Sizes for Insomnia.Journal of sleep research · 2026Article
- Emerging genetics of sleep and circadian disorders.Current opinion in pediatrics · 2026Article
- Population-Specific Genetic and Non-Genetic Influences on Sleep Traits and Health Outcomes.ArXiv · 2026Article
- Restless Legs Syndrome: A Network Model of Iron-Dependent Neuromodulation-A Narrative Review.Brain sciences · 2026Review
- Genome-wide association study of restless legs syndrome in end-stage renal disease.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Article
- Vimentin network dysregulation mediates neurite deficits inScience advances · 2025Article
- Unraveling Restless Legs Syndrome: A Comprehensive Review of Current Research and Future Directions.International journal of general medicine · 2025Review
- RLS-associated MEIS transcription factors control distinct processes in human neural stem cells.Scientific reports · 2024Article
- BS-clock, advancing epigenetic age prediction with high-resolution DNA methylation bisulfite sequencing data.Bioinformatics (Oxford, England) · 2024Article
- Article
- A primate nigrostriatal atlas of neuronal vulnerability and resilience in a model of Parkinson's disease.Nature communications · 2023Article
- Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep.Science advances · 2023Article
- Is Restless Legs Syndrome De Facto Thyroid Disease?Biomedicines · 2022Article
- Interpretation of network-based integration from multi-omics longitudinal data.Nucleic acids research · 2022Article
- StarGazer: A Hybrid Intelligence Platform for Drug Target Prioritization and Digital Drug Repositioning Using Streamlit.Frontiers in genetics · 2022Article
- Genome-Wide Association Study and Genetic Correlation Scan Provide Insights into Its Genetic Architecture of Sleep Health Score in the UK Biobank Cohort.Nature and science of sleep · 2022Article
- Restless legs syndrome.Nature reviews. Disease primers · 2021Review
- Association of proton pump inhibitor and histamine H2-receptor antagonists with restless legs syndrome.Sleep · 2021Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Restless legs syndrome (RLS) is a common sleep-related disorder for which the underlying biological pathways and genetic determinants are not well understood. The genetic factors so far identified explain less than 10% of the disease heritability. The first successful genome-wide association study (GWAS) of RLS was reported in 2007. This study identified multiple RLS associated risk variants including some within the non-coding regions of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.