Evidence map›Paper›PMID 31551809›Full record

ArticleFrontiers in physiology2019

Upregulation of miR-133b and miR-328 in Patients With Atrial Dilatation: Implications for Stretch-Induced Atrial Fibrillation.

Michela Masè, Margherita Grasso, Laura Avogaro, Manuel Nicolussi Giacomaz, Elvira D'Amato, Francesco Tessarolo, Angelo Graffigna, Michela Alessandra Denti, Flavia Ravelli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Analysis of miRNAs inPharmaceuticals (Basel, Switzerland) · 2023
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Atrial Fibrillation: Pathogenesis, Predisposing Factors, and Genetics.International journal of molecular sciences · 2021
    Review
  8. Review
  9. Role of the microRNA-29 family in myocardial fibrosis.Journal of physiology and biochemistry · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Genome-wide analysis of circular RNA expression profiles in patients with atrial fibrillation.International journal of clinical and experimental pathology · 2020
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Michela MasèLaboratory of Biophysics and Biosignals, University of Trento, Trento, Italy.
Margherita GrassoDepartment of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
Laura AvogaroDepartment of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
Manuel Nicolussi GiacomazDepartment of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
Elvira D'AmatoLaboratory of Biophysics and Biosignals, University of Trento, Trento, Italy.
Francesco TessaroloHealthcare Research and Innovation Program, Bruno Kessler Foundation, Trento, Italy.
Angelo GraffignaDivision of Cardiac Surgery, Santa Chiara Hospital, Trento, Italy.
Michela Alessandra DentiDepartment of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
Flavia RavelliLaboratory of Biophysics and Biosignals, University of Trento, Trento, Italy.
University of Trento · ITFondazione Bruno Kessler · ITOspedale Santa Chiara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial stretch and dilatation are common features of many clinical conditions predisposing to atrial fibrillation (AF). MicroRNAs (miRs) are emerging as potential molecular determinants of AF, but their relationship with atrial dilatation (AD) is poorly understood. The present study was designed to assess the specific miR expression profiles associated with AD in human atrial tissue. The expressions of a preselected panel of miRs, previously described as playing a role in cardiac disease, were quantified by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) in atrial tissue samples from 30 cardiac surgery patients, who were characterized by different grades of AD and arrhythmic profiles. Our results showed that AD

Indexed as

arrhythmic substrateatrial fibrillationatrial remodelingchronic stretchmicroRNApost-transcriptional regulation

Identifiers

PMID31551809
PMCPMC6748158
OpenAlexW2967496595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.