Evidence map›Paper›PMID 31551808›Full record

ArticleFrontiers in physiology2019

Cardiotonic Pills Plus Recombinant Human Prourokinase Ameliorates Atherosclerotic Lesions in LDLR

Jing-Na Deng, Quan Li, Kai Sun, Chun-Shui Pan, Huan Li, Jing-Yu Fan, Gao Li, Bai-He Hu, Xin Chang, Jing-Yan Han

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jing-Na DengDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.
Quan LiTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.
Kai SunTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.
Chun-Shui PanTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.
Huan LiDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.
Jing-Yu FanTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.
Gao LiDepartment of Oncology, Guizhou University of Chinese Medicine, Guiyang, China.
Bai-He HuTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.
Xin ChangTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.
Jing-Yan HanDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.
State Administration of Traditional Chinese Medicine of the People's Republic of China · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study was to explore the protective effects of cardiotonic pills (CP) or/and recombinant human prourokinase (proUK)on the atherosclerosis and the potential underlying mechanism. METHODS AND

resultsAtherosclerosis was induced in LDLR

conclusionCP plus proUK effectively attenuated atherosclerosis plaque in LDLR

Indexed as

adipose triglyceride lipaseatherosclerosisATP-binding cassette gene 8CD36inflammationscavenger receptor A

Identifiers

PMID31551808
PMCPMC6747059
OpenAlexW2967927829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.